Evidence map›Paper›PMID 33182781›Full record

ArticleInternational journal of molecular sciences2020

Negative Regulation of the Differentiation of Flk2

Chun-Hao Hung, Keh-Yang Wang, Yae-Huei Liou, Jing-Ping Wang, Anna Yu-Szu Huang, Tung-Liang Lee, Si-Tse Jiang, Nah-Shih Liao, Yu-Chiau Shyu, Che-Kun James Shen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Chun-Hao HungInstitute of Molecular Biology, Academia Sinica, Nankang, Taipei 115, Taiwan.
Keh-Yang WangInstitute of Molecular Biology, Academia Sinica, Nankang, Taipei 115, Taiwan.
Yae-Huei LiouInstitute of Molecular Biology, Academia Sinica, Nankang, Taipei 115, Taiwan.
Jing-Ping WangInstitute of Molecular Biology, Academia Sinica, Nankang, Taipei 115, Taiwan.
Anna Yu-Szu HuangInstitute of Molecular Biology, Academia Sinica, Nankang, Taipei 115, Taiwan.
Tung-Liang LeeInstitute of Molecular Biology, Academia Sinica, Nankang, Taipei 115, Taiwan.
Si-Tse JiangDepartment of Research and Development, National Laboratory Animal Center, National Applied Research Laboratories, Tainan 74147, Taiwan.
Nah-Shih LiaoInstitute of Molecular Biology, Academia Sinica, Nankang, Taipei 115, Taiwan.ORCID 0000-0003-3707-4145
Yu-Chiau ShyuInstitute of Molecular Biology, Academia Sinica, Nankang, Taipei 115, Taiwan.ORCID 0000-0003-1747-2226
Che-Kun James ShenInstitute of Molecular Biology, Academia Sinica, Nankang, Taipei 115, Taiwan.
Institute of Molecular Biology, Academia Sinica · TWChang Gung University of Science and Technology · TWNational Institutes of Applied Research · TW

Funding

National Health Research Institute and MOST grant NHRI-EX103-10011SI and NSC 102-2320-B-001-MY3
6 · The paper itself

Abstract

Erythroid Krüppel-like factor (EKLF/KLF1) was identified initially as a critical erythroid-specific transcription factor and was later found to be also expressed in other types of hematopoietic cells, including megakaryocytes and several progenitors. In this study, we have examined the regulatory effects of EKLF on hematopoiesis by comparative analysis of E14.5 fetal livers from wild-type and

Indexed as

AnimalsAntigens, CD34Cell DifferentiationCell LineageCells, CulturedCytokine Receptor Common beta Subunitfms-Like Tyrosine Kinase 3HematopoiesisHematopoietic Stem CellsHematopoietic Stem Cell TransplantationHomeostasisKruppel-Like Transcription FactorsLiverMiceMice, Inbred C57BLMice, KnockoutAntigens, CD34Csf2rb protein, mouseCytokine Receptor Common beta Subuniterythroid Kruppel-like factorFlt3 protein, mousefms-Like Tyrosine Kinase 3Kruppel-Like Transcription FactorsRNA, MessengerdifferentiationEKLF/KLF1Flk2-CD34-HSChematopoiesis

Identifiers

PMID33182781
PMCPMC7697791
OpenAlexW3102972838

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.