Evidence map›Paper›PMID 33182716›Full record

ArticleInternational journal of molecular sciences2020

BDNF rs6265 Polymorphism and Its Methylation in Patients with Stroke Undergoing Rehabilitation.

Massimo Santoro, Mariacristina Siotto, Marco Germanotta, Elisa Bray, Alessia Mastrorosa, Camilla Galli, Dionysia Papadopoulou, Irene Aprile

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04923165 (Influence of Nutritional Status on Rehabilitation Outcome in Subacute Stroke Patients), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04923165 completednot on this map

Influence of Nutritional Status on Rehabilitation Outcome in Subacute Stroke Patients

TypeobservationalSponsorFondazione Don Carlo Gnocchi ETSRan2020 to 2023Enrolled119ConditionsStrokeArmsrobotic assisted intervention, biochemical analyses, BIA, hand grip, nutritional assessment, MNA
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
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  6. Review
  7. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Massimo SantoroIRCCS Fondazione Don Carlo Gnocchi ONLUS, 50143 Florence, Italy.ORCID 0000-0002-3037-2775
Mariacristina SiottoIRCCS Fondazione Don Carlo Gnocchi ONLUS, 50143 Florence, Italy.ORCID 0000-0003-0837-0594
Marco GermanottaIRCCS Fondazione Don Carlo Gnocchi ONLUS, 50143 Florence, Italy.ORCID 0000-0002-0747-831X
Elisa BrayIRCCS Fondazione Don Carlo Gnocchi ONLUS, 50143 Florence, Italy.
Alessia MastrorosaIRCCS Fondazione Don Carlo Gnocchi ONLUS, 50143 Florence, Italy.
Camilla GalliIRCCS Fondazione Don Carlo Gnocchi ONLUS, 50143 Florence, Italy.
Dionysia PapadopoulouIRCCS Fondazione Don Carlo Gnocchi ONLUS, 50143 Florence, Italy.
Irene AprileIRCCS Fondazione Don Carlo Gnocchi ONLUS, 50143 Florence, Italy.
Don Carlo Gnocchi Foundation · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain-Derived Neurotrophic Factor (BDNF) and its rs6265 single nucleotide polymorphism (SNP) play an important role in post-stroke recovery. We investigated the correlation between

Indexed as

Polymorphism, Single NucleotideStroke RehabilitationAgedAged, 80 and overBrain-Derived Neurotrophic FactorCpG IslandsDNA MethylationFemaleGenetic MarkersHeterozygoteHomozygoteHumansLogistic ModelsMaleMiddle AgedPrognosisBDNF protein, humanBrain-Derived Neurotrophic FactorGenetic MarkersBDNFBDNF rs6265 methylationBDNF rs6265 polymorphismrehabilitationstroke

Identifiers

PMID33182716
PMCPMC7696026
OpenAlexW3100307382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.