ArticleJournal of clinical medicine2020
Differentiated Thyroid Cancer in Children in the Last 20 Years: A Regional Study in Romania.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Survival Trends in Pediatric Differentiated Thyroid Cancer: A Middle Eastern Perspective.Life (Basel, Switzerland) · 2024Article
- Risk factors of postoperative hypoparathyroidism after total thyroidectomy in pediatric patients with thyroid cancer.Annals of pediatric endocrinology & metabolism · 2023Article
- Role of Dietary and Environmental Factors on Thyroid Cancer in Romania: A Brief Review.Diagnostics (Basel, Switzerland) · 2022Review
- Tumor size is an independent negative prognostic factor for event free survival in children with differentiated thyroid cancer.Frontiers in endocrinology · 2022Article
- Thyroid Microcarcinoma in Pediatric Population in Romania.Children (Basel, Switzerland) · 2021Article
- Updated Incidence of Thyroid Cancer in the North East Region of Romania after 35 Years of Chernobyl Fallout. Is There a Link between?Diagnostics (Basel, Switzerland) · 2021Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pediatric thyroid carcinoma is a current area of interest, because there are few studies in this field; the current classification and treatment guidelines are extrapolated from adults, sometimes leading to overly aggressive treatments or incomplete treatment of the disease. The purpose of this retrospective study is to analyze the presentation, diagnosis, treatment, complications, and outcome of children diagnosed with thyroid cancer in the last two decades (2000-2018) at the Oncological Institute "Prof. Dr. Ion Chiricuță" Cluj-Napoca (IOCN) Romania, a tertiary center in a region with environmental influences from both the nuclear fallout of the Chernobyl accident and from iodine deficiency. The results were compared with those obtained in a previous study carried out in the same institution between 1991-2010, and with those obtained in a similar study carried out in Netherlands between 1970-2013, a cohort of children not exposed to the post-Chernobyl fallout. We statistically analyzed 62 patients. Papillary form was present in the majority of cases, and we highlighted the occurrence of thyroid microcarcinoma in children. A total of 85.4% of patients received radioiodine, the total activity being significantly lower compared with the data from literature. In our study, the prognosis of the disease was excellent, with 100% overall survival.
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Registered trials
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