Evidence map›Paper›PMID 33182592›Full record

ArticleJournal of clinical medicine2020

Association of the Hemoglobin to Serum Creatinine Ratio with In-Hospital Adverse Outcomes after Percutaneous Coronary Intervention among Non-Dialysis Patients: Insights from a Japanese Nationwide Registry (J-PCI Registry).

Yohei Numasawa, Taku Inohara, Hideki Ishii, Kyohei Yamaji, Shun Kohsaka, Mitsuaki Sawano, Masaki Kodaira, Shiro Uemura, Kazushige Kadota, Tetsuya Amano and 2 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Association between hemoglobin-to-creatinine ratio and all-cause mortality in patients with coronary artery disease.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Article
  4. The Negative Influence and Adverse Outcome of Red Blood Cell Transfusion in Contemporary Percutaneous Coronary Interventions.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Analysis of the Correlation Between the Ratio of Monocytes to High-Density Lipoprotein Cholesterol and in-Stent Restenosis in Patients with Premature Coronary Heart Disease.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yohei NumasawaDepartment of Cardiology, Japanese Red Cross Ashikaga Hospital, 284-1 Yobe-cho, Ashikaga, Tochigi 326-0843, Japan.ORCID 0000-0002-1739-2800
Taku InoharaDepartment of Cardiology, Keio University School of Medicine, Tokyo 160-8582, Japan.
Hideki IshiiDepartment of Cardiology, Fujita Health University Bantane Hospital, Nagoya 454-8509, Japan.ORCID 0000-0003-4348-0123
Kyohei YamajiDepartment of Cardiology, Kokura Memorial Hospital, Kitakyushu 802-8555, Japan.ORCID 0000-0002-8798-9186
Shun KohsakaDepartment of Cardiology, Keio University School of Medicine, Tokyo 160-8582, Japan.ORCID 0000-0003-3779-2972
Mitsuaki SawanoDepartment of Cardiology, Keio University School of Medicine, Tokyo 160-8582, Japan.ORCID 0000-0003-2789-1758
Masaki KodairaDepartment of Cardiology, Japanese Red Cross Ashikaga Hospital, 284-1 Yobe-cho, Ashikaga, Tochigi 326-0843, Japan.
Shiro UemuraDepartment of Cardiology, Kawasaki Medical School, Kurashiki 701-0192, Japan.
Kazushige KadotaDepartment of Cardiology, Kurashiki Central Hospital, Kurashiki 710-8602, Japan.
Tetsuya AmanoDepartment of Cardiology, Aichi Medical University, Nagakute 480-1195, Japan.
Masato NakamuraDivision of Cardiovascular Medicine, Toho University Ohashi Medical Center, Tokyo 153-8515, Japan.
Yuji IkariDivision of Cardiology, Tokai University School of Medicine, Isehara 259-1193, Japan.ORCID 0000-0001-5686-4324

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although baseline hemoglobin and renal function are both important predictors of adverse outcomes after percutaneous coronary intervention (PCI), scarce data exist regarding the combined impact of these factors on outcomes. We sought to investigate the impact and threshold value of the hemoglobin to creatinine (Hgb/Cr) ratio, on in-hospital adverse outcomes among non-dialysis patients in a Japanese nationwide registry. We analyzed 157,978 non-dialysis patients who underwent PCI in 884 Japanese medical institutions in 2017. We studied differences in baseline characteristics and in-hospital clinical outcomes among four groups according to their quartiles of the Hgb/Cr ratios. Compared with patients with higher Hgb/Cr ratios, patients with lower ratios were older and had more comorbidities and complex coronary artery disease. Patients with lower hemoglobin and higher creatinine levels had a higher rate of in-hospital adverse outcomes including in-hospital mortality and procedural complications (defined as occurrence of cardiac tamponade, cardiogenic shock after PCI, emergency operation, or bleeding complications that required blood transfusion). On multivariate analyses, Hgb/Cr ratio was inversely associated with in-hospital mortality (odds ratio: 0.91, 95% confidence interval: 0.89-0.92;

Indexed as

anemiachronic kidney diseasecreatininehemoglobinpercutaneous coronary intervention

Identifiers

PMID33182592
PMCPMC7696709

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.