ArticleBiology2020
Development of Open-Field Behaviour in the Medaka,
Article in Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 26 citations in OpenAlex.
- Divergent spatiotemporal integration of whole-field visual motion in medaka and zebrafish.bioRxiv : the preprint server for biology · 2025Article
- Measurement and classification of bold-shy behaviours in medaka fish.Bioinformatics (Oxford, England) · 2025Article
- Assessing Chronodisruption Distress in Goldfish: The Importance of Multimodal Approaches.Animals : an open access journal from MDPI · 2023Article
- First report on the toxicity of SARS-CoV-2, alone and in combination with polyethylene microplastics in neotropical fish.The Science of the total environment · 2023Article
- Enhancing Rearing of European Seabass (Animals : an open access journal from MDPI · 2023Article
- Teleosts as behaviour test models for social stress.Frontiers in behavioral neuroscience · 2023Review
- Neuropeptide Y receptor Y2 (Frontiers in cell and developmental biology · 2023Article
- Age-related alterations in the behavioral response to a novel environment in the African turquoise killifish (Frontiers in behavioral neuroscience · 2023Article
- Article
- Comparison of anxiety-like and social behaviour in medaka and zebrafish.Scientific reports · 2022Article
- Environmental enrichment decreases anxiety-like behavior in zebrafish larvae.Developmental psychobiology · 2022Article
- Interspecies Behavioral Variability of Medaka Fish Assessed by Comparative Phenomics.International journal of molecular sciences · 2021Article
- Characterization ofFrontiers in physiology · 2021Article
- Cognitive individual differences are key in the network of trait covariance.Behavioral ecology : official journal of the International Society for Behavioral EcologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
The use of juvenile and larval fish models has been growing in importance for several fields. Accordingly, the evaluation of behavioural tests that can be applied to larvae and juveniles is becoming increasingly important. We tested medaka at four different ages (1, 10, 30, and 120 dph) in the open field test, one of the most commonly used behavioural assays, to investigate its suitability for larvae and juveniles of this species. We also explored ontogenetic variation in behaviour during this test. On average, adult 120-day-old medaka showed higher locomotor activity in terms of distance moved compared with younger fish. Our analysis suggests that this effect was derived from both quantitative changes in locomotion related to the ontogenetic increase in fish size as well as qualitative changes in two aspects of locomotor behaviour. Specifically, time spent moving was similar between 1- and 10-day-old medaka, but progressively increased with development. In addition, we revealed that adult medaka showed constant levels of activity, whereas younger medaka progressively reduced their activity over the course of the entire experiment. The thigmotaxis behaviour typically used to assess anxiety in the open field test emerged at 120 days post-hatching, even though a difference in the temporal pattern of spatial preference emerged earlier, between 10 and 30 days post-hatching. In conclusion, some measures of the open field test such as total distance moved allow behavioural phenotyping in the medaka of all ages, although with some degree of quantitative and qualitative developmental variation. In contrast, immature medaka appear not to exhibit thigmotactic behaviour.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.