Evidence map›Paper›PMID 33182541›Full record

ArticleInternational journal of molecular sciences2020

Translational Read-Through Therapy of

Christine Vössing, Marta Owczarek-Lipska, Kerstin Nagel-Wolfrum, Charlotte Reiff, Christoph Jüschke, John Neidhardt

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. A human-specificMolecular therapy. Nucleic acids · 2025
    Article
  3. Molecular treatment options for patients carryingMolecular therapy. Nucleic acids · 2025
    Article
  4. Article
  5. Article
  6. Medicina (Kaunas, Lithuania) · 2024
    Article
  7. Article
  8. Morphological Observation and Transcriptome Analysis of Ciliogenesis inInternational journal of molecular sciences · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. The Potential Effect of NaFrontiers in molecular neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Christine VössingHuman Genetics, Faculty of Medicine and Health Sciences, University of Oldenburg, 26129 Oldenburg, Germany.
Marta Owczarek-LipskaHuman Genetics, Faculty of Medicine and Health Sciences, University of Oldenburg, 26129 Oldenburg, Germany.ORCID 0000-0001-6667-4452
Kerstin Nagel-WolfrumInstitute of Developmental Biology and Neurobiology, Johannes Gutenberg-University of Mainz, 55099 Mainz, Germany.
Charlotte ReiffEye Center, Albert-Ludwigs-University of Freiburg, 79106 Freiburg, Germany.
Christoph JüschkeHuman Genetics, Faculty of Medicine and Health Sciences, University of Oldenburg, 26129 Oldenburg, Germany.
John NeidhardtHuman Genetics, Faculty of Medicine and Health Sciences, University of Oldenburg, 26129 Oldenburg, Germany.
Carl von Ossietzky Universität Oldenburg · DEJohannes Gutenberg University Mainz · DEUniversity of Freiburg · DE

Funding

Deutsche Forschungsgemeinschaft 1885/1-2Deutsche Forschungsgemeinschaft NA 1398/1-1ERARE17-114 NE 2118/2-1FAUN Stiftung -
6 · The paper itself

Abstract

X-chromosomal retinitis pigmentosa (RP) frequently is caused by mutations in the retinitis pigmentosa GTPase regulator (

Indexed as

Case-Control StudiesCells, CulturedCiliaCodon, NonsenseEye ProteinsGenetic Diseases, X-LinkedHEK293 CellsHemizygoteHumansMutant ProteinsOxadiazolesProof of Concept StudyProtein BiosynthesisRetinitis PigmentosaRNA StabilityatalurenCodon, NonsenseEye ProteinsMutant ProteinsOxadiazolesRPGR protein, humanAtalurenciliaciliumnonsense mutationPTC124read-through therapyRPGRstop mutationtranscriptional therapytreatment

Identifiers

PMID33182541
PMCPMC7697989
OpenAlexW3103423453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.