Evidence map›Paper›PMID 33182525›Full record

ArticleCancers2020

Role of miRNAs in Sigmoid Colon Cancer: A Search for Potential Biomarkers.

Diego Marques, Layse Raynara Ferreira-Costa, Lorenna Larissa Ferreira-Costa, Ana Beatriz Bezerra-Oliveira, Romualdo da Silva Correa, Carlos Cesar de Oliveira Ramos, Tatiana Vinasco-Sandoval, Katia de Paiva Lopes, Ricardo Assunção Vialle, Amanda Ferreira Vidal and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Diego MarquesLaboratório de Genética Humana e Médica, Universidade Federal do Pará, Av. Augusto Corrêa, 01, Guamá, Belém 66.075-110, Brazil.ORCID 0000-0002-7446-6087
Layse Raynara Ferreira-CostaLaboratório de Bioanálise e Biotecnologia Molecular, Universidade Federal do Rio Grande do Norte, Av. Nilo Peçanha, 620, Petrópolis, Natal 59012-300, Brazil.
Lorenna Larissa Ferreira-CostaLaboratório de Bioanálise e Biotecnologia Molecular, Universidade Federal do Rio Grande do Norte, Av. Nilo Peçanha, 620, Petrópolis, Natal 59012-300, Brazil.
Ana Beatriz Bezerra-OliveiraLaboratório de Bioanálise e Biotecnologia Molecular, Universidade Federal do Rio Grande do Norte, Av. Nilo Peçanha, 620, Petrópolis, Natal 59012-300, Brazil.
Romualdo da Silva CorreaDepartamento de Cirurgia Oncológica, Liga Norte Riograndense Contra o Câncer, R. Mário Negócio, 2267, Quintas, Natal 59040-000, Brazil.
Carlos Cesar de Oliveira RamosLaboratório de Patologia e Citopatologia, Liga Norte Riograndense Contra o Câncer, R. Mário Negócio, 2267, Quintas, Natal 59040-000, Brazil.
Tatiana Vinasco-SandovalLaboratório de Genética Humana e Médica, Universidade Federal do Pará, Av. Augusto Corrêa, 01, Guamá, Belém 66.075-110, Brazil.ORCID 0000-0002-0189-0573
Katia de Paiva LopesLaboratório de Genética Humana e Médica, Universidade Federal do Pará, Av. Augusto Corrêa, 01, Guamá, Belém 66.075-110, Brazil.ORCID 0000-0002-0240-0126
Ricardo Assunção VialleLaboratório de Genética Humana e Médica, Universidade Federal do Pará, Av. Augusto Corrêa, 01, Guamá, Belém 66.075-110, Brazil.ORCID 0000-0003-3311-4197
Amanda Ferreira VidalLaboratório de Genética Humana e Médica, Universidade Federal do Pará, Av. Augusto Corrêa, 01, Guamá, Belém 66.075-110, Brazil.ORCID 0000-0003-4180-9925
Vivian Nogueira SilbigerLaboratório de Bioanálise e Biotecnologia Molecular, Universidade Federal do Rio Grande do Norte, Av. Nilo Peçanha, 620, Petrópolis, Natal 59012-300, Brazil.ORCID 0000-0002-9252-0278
Ândrea Ribeiro-Dos-SantosLaboratório de Genética Humana e Médica, Universidade Federal do Pará, Av. Augusto Corrêa, 01, Guamá, Belém 66.075-110, Brazil.ORCID 0000-0001-7001-1483
Universidade Federal do Pará · BRUniversidade Federal do Rio Grande do Norte · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), 306815/2018-4 and 483031/2013-5Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) - Rede de Pesquisa em Genômica Populacional Humana Biocomputacional/CAPES-051/2013Fundação de Amparo à Pesquisa do Estado do Rio Grande do Norte 005/2011
6 · The paper itself

Abstract

The aberrant expression of microRNAs in known to play a crucial role in carcinogenesis. Here, we evaluated the miRNA expression profile of sigmoid colon cancer (SCC) compared to adjacent-to-tumor (ADJ) and sigmoid colon healthy (SCH) tissues obtained from colon biopsy extracted from Brazilian patients. Comparisons were performed between each group separately, considering as significant

Indexed as

biomarkerscolorectal cancerfield-effectmiRNome

Identifiers

PMID33182525
PMCPMC7697997
OpenAlexW3104363616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.