Evidence map›Paper›PMID 33182511›Full record

ArticleCancers2020

Unsupervised Hierarchical Clustering of Pancreatic Adenocarcinoma Dataset from TCGA Defines a Mucin Expression Profile that Impacts Overall Survival.

Nicolas Jonckheere, Julie Auwercx, Elsa Hadj Bachir, Lucie Coppin, Nihad Boukrout, Audrey Vincent, Bernadette Neve, Mathieu Gautier, Victor Treviño, Isabelle Van Seuningen

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  11. MgNutrients · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Nicolas JonckheereUniv. Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity Plasticity and Resistance to Therapies, F-59000 Lille, France.ORCID 0000-0002-0496-0661
Julie AuwercxUniv. Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity Plasticity and Resistance to Therapies, F-59000 Lille, France.ORCID 0000-0002-5873-4838
Elsa Hadj BachirUniv. Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity Plasticity and Resistance to Therapies, F-59000 Lille, France.
Lucie CoppinUniv. Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity Plasticity and Resistance to Therapies, F-59000 Lille, France.ORCID 0000-0002-6596-720X
Nihad BoukroutUniv. Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity Plasticity and Resistance to Therapies, F-59000 Lille, France.
Audrey VincentUniv. Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity Plasticity and Resistance to Therapies, F-59000 Lille, France.ORCID 0000-0003-0058-2058
Bernadette NeveUniv. Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity Plasticity and Resistance to Therapies, F-59000 Lille, France.ORCID 0000-0003-1516-1379
Mathieu GautierLaboratoire de Physiologie Cellulaire et Moléculaire-UR UPJV 4667, UFR Sciences, Université de Picardie Jules Verne (UPJV), 80039 Amiens, France.ORCID 0000-0001-8971-5683
Victor TreviñoCátedra de Bioinformática, Escuela de Medicina, Tecnologico de Monterrey, Monterrey 64710, Nuevo León, Mexico.ORCID 0000-0002-7472-9844
Isabelle Van SeuningenUniv. Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity Plasticity and Resistance to Therapies, F-59000 Lille, France.ORCID 0000-0002-3131-2694
Centre National de la Recherche Scientifique · FRLaboratoire de physiologie cellulaire et moléculaire · FRTecnológico de Monterrey · MX

Funding

Institut National de la Santé et de la Recherche Médicale; Centre National de la Recherche Scientifique;Ligue Nationale contre le Cancer none
6 · The paper itself

Abstract

Mucins are commonly associated with pancreatic ductal adenocarcinoma (PDAC) that is a deadly disease because of the lack of early diagnosis and efficient therapies. There are 22 mucin genes encoding large

Indexed as

gene signaturemucinoverall survivalpancreatic cancerTCGAunsupervised hierarchical clustering

Identifiers

PMID33182511
PMCPMC7697168
OpenAlexW3098284860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.