Evidence map›Paper›PMID 33182484›Full record

ArticleInternational journal of molecular sciences2020

High Stroma T-Cell Infiltration is Associated with Better Survival in Stage pT1 Bladder Cancer.

Sabine Hülsen, Eleonora Lippolis, Fulvia Ferrazzi, Wolfgang Otto, Luitpold Distel, Rainer Fietkau, Stefan Denzinger, Johannes Breyer, Maximilian Burger, Simone Bertz and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

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  14. Cell Therapies in Bladder Cancer Management.International journal of molecular sciences · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Sabine HülsenInstitute of Pathology, Friedrich-Alexander-University, Erlangen-Nürnberg, 91054 Erlangen, Germany.
Eleonora LippolisInstitute of Human Genetics, Friedrich-Alexander-University, Erlangen-Nürnberg, 91054 Erlangen, Germany.
Fulvia FerrazziInstitute of Pathology, Friedrich-Alexander-University, Erlangen-Nürnberg, 91054 Erlangen, Germany.ORCID 0000-0003-4011-4638
Wolfgang OttoCaritas St. Josef Medical Center, Department of Urology, Regensburg University, 93053 Regensburg, Germany.
Luitpold DistelDepartment of Radiation Therapy, Friedrich-Alexander-University, Erlangen-Nürnberg, 91054 Erlangen, Germany.ORCID 0000-0002-8040-3226
Rainer FietkauDepartment of Radiation Therapy, Friedrich-Alexander-University, Erlangen-Nürnberg, 91054 Erlangen, Germany.
Stefan DenzingerCaritas St. Josef Medical Center, Department of Urology, Regensburg University, 93053 Regensburg, Germany.
Johannes BreyerCaritas St. Josef Medical Center, Department of Urology, Regensburg University, 93053 Regensburg, Germany.
Maximilian BurgerCaritas St. Josef Medical Center, Department of Urology, Regensburg University, 93053 Regensburg, Germany.
Simone BertzInstitute of Pathology, Friedrich-Alexander-University, Erlangen-Nürnberg, 91054 Erlangen, Germany.ORCID 0000-0003-0458-7075
Markus EcksteinInstitute of Pathology, Friedrich-Alexander-University, Erlangen-Nürnberg, 91054 Erlangen, Germany.
Annette EbnerInstitute of Pathology, Friedrich-Alexander-University, Erlangen-Nürnberg, 91054 Erlangen, Germany.
Arndt HartmannInstitute of Pathology, Friedrich-Alexander-University, Erlangen-Nürnberg, 91054 Erlangen, Germany.ORCID 0000-0002-4860-4626
Carol-I GeppertInstitute of Pathology, Friedrich-Alexander-University, Erlangen-Nürnberg, 91054 Erlangen, Germany.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stage pT1 bladder cancer (BC) shows highly diverse outcomes. Predictive markers are required to stratify patients for personalized treatment. The present study aimed to validate immune response quantification as a prognostic marker. Patients with pT1 BC (

Indexed as

AdultAgedAged, 80 and overBiomarkersCD3 ComplexCD8-Positive T-LymphocytesFemaleHumansLymphocytes, Tumor-InfiltratingMaleMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingPrognosisTumor MicroenvironmentUrinary Bladder NeoplasmsBiomarkersCD3 ComplexCD8+ lymphocytesimmunoscoreprogressionpT1 bladder cancersurvivaltumor-infiltrating lymphocytes (TILs), CD3+ lymphocytes

Identifiers

PMID33182484
PMCPMC7665154
OpenAlexW3099215850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.