Evidence map›Paper›PMID 33182366›Full record

ArticleMolecules (Basel, Switzerland)2020

Biomimetic Alginate/Gelatin Cross-Linked Hydrogels Supplemented with Polyphosphate for Wound Healing Applications.

Shunfeng Wang, Xiaohong Wang, Meik Neufurth, Emad Tolba, Hadrian Schepler, Shichu Xiao, Heinz C Schröder, Werner E G Müller

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  5. Gelatin-sodium alginate hydrogel infused withBiochemistry and biophysics reports · 2025
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  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Shunfeng WangERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany.
Xiaohong WangERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany.ORCID 0000-0003-1796-6314
Meik NeufurthERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany.ORCID 0000-0002-2383-6412
Emad TolbaERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany.
Hadrian ScheplerDepartment of Dermatology, University Clinic Mainz, Langenbeckstr. 1, D-55131 Mainz, Germany.
Shichu XiaoShanghai Changhai Hospital, No. 168 Changhai Road, Yangpu District, Shanghai 200000, China.
Heinz C SchröderERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany.ORCID 0000-0003-0992-6427
Werner E G MüllerERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany.ORCID 0000-0002-8223-3689
Johannes Gutenberg University Mainz · DESecond Military Medical University · CN

Funding

Bundesministerium für Forschung und Technologie 13GW0403B
6 · The paper itself

Abstract

In the present study, the fabrication of a biomimetic wound dressing that mimics the extracellular matrix, consisting of a hydrogel matrix composed of non-oxidized and periodate-oxidized marine alginate, was prepared to which gelatin was bound via Schiff base formation. Into this alginate/oxidized-alginate-gelatin hydrogel, polyP was stably but reversibly integrated by ionic cross-linking with Zn

Indexed as

BiomimeticsWound HealingAlginatesBiocompatible MaterialsCell MovementCell SurvivalEpidermisExtracellular MatrixGelatinHumansHydrogelsHydrogen-Ion ConcentrationIonsKeratinocytesMetal NanoparticlesNanoparticlesAlginatesBiocompatible MaterialsGelatinHydrogelsIonsPolyphosphatesZincalginatecell migrationcoacervategelatinhuman epidermal keratinocytesinorganic polyphosphateionic cross-linkingnanoparticlesperiodate oxidationzinc ions

Identifiers

PMID33182366
PMCPMC7664853
OpenAlexW3104556257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.