Evidence map›Paper›PMID 33182355›Full record

ArticleMicroorganisms2020

Madhur D Shastri, Wai Chin Chong, Ravichandra Vemuri, Christopher J Martoni, Santosh Adhikari, Harinder Bhullar, Dale Kunde, Stephen G Tristram, Rajaraman D Eri

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Madhur D ShastriSchool of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston 7250, Australia.
Wai Chin ChongDepartment of Molecular and Translational Science, Monash University, Clayton 3800, Australia.
Ravichandra VemuriSchool of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston 7250, Australia.ORCID 0000-0002-3238-426X
Christopher J MartoniUAS Laboratories, Madison, Windsor, WI 53598, USA.
Santosh AdhikariSchool of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston 7250, Australia.
Harinder BhullarSchool of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston 7250, Australia.
Dale KundeSchool of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston 7250, Australia.
Stephen G TristramSchool of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston 7250, Australia.ORCID 0000-0002-8485-0322
Rajaraman D EriSchool of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston 7250, Australia.ORCID 0000-0003-1688-8043
University of Tasmania · AUMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotics have been widely used in maintaining gastrointestinal health, despite their actual mechanism remaining obscure. There are several hypotheses behind the beneficial effects of probiotics including the regulation of intestinal barrier function and improvement in immune responses in the gastrointestinal system. Multiple probiotics have been introduced in the market as effective dietary supplements in improving gastrointestinal integrity, but there are no or few studies that demonstrate their underlying mechanism. In the current study, we investigated and compared the efficacy of four probiotics (based on different bacterial species) in refining gastrointestinal health by improving mucus biosynthesis and intestinal immune response under in-vitro conditions. By analyzing the gene expression of mucus biosynthesis and intestinal immune response markers, we found that probiotic

Indexed as

goblet cellsimmunomodulationintestinal peptidesMucin-2probiotics

Identifiers

PMID33182355
PMCPMC7695341
OpenAlexW3101223944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.