Evidence map›Paper›PMID 33182307›Full record

ArticleInternational journal of molecular sciences2020

Human Microfibrillar-Associated Protein 4 (MFAP4) Gene Promoter: A TATA-Less Promoter That Is Regulated by Retinol and Coenzyme Q10 in Human Fibroblast Cells.

Ying-Ju Lin, An-Ni Chen, Xi Jiang Yin, Chunxiang Li, Chih-Chien Lin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Ying-Ju LinSchool of Chinese Medicine, China Medical University, Taichung 40447, Taiwan.
An-Ni ChenDepartment of Cosmetic Science, Providence University, Taichung 43301, Taiwan.
Xi Jiang YinAdvanced Materials Technology Centre, Singapore Polytechnic, Singapore 139651, Singapore.
Chunxiang LiAdvanced Materials Technology Centre, Singapore Polytechnic, Singapore 139651, Singapore.ORCID 0000-0003-1257-8160
Chih-Chien LinDepartment of Cosmetic Science, Providence University, Taichung 43301, Taiwan.ORCID 0000-0002-4664-2995
Providence University · TWSingapore Polytechnic · SGChina Medical University · TW

Funding

Ministry of Science and Technology, Taiwan MOST 105-2628-B-126-002-MY3Ministry of Science and Technology, Taiwan MOST 108-2313-B-126-001Ministry of Science and Technology, Taiwan MOST 109-2313-B-126-002
6 · The paper itself

Abstract

Elastic fibers are one of the major structural components of the extracellular matrix (ECM) in human connective tissues. Among these fibers, microfibrillar-associated protein 4 (MFAP4) is one of the most important microfibril-associated glycoproteins. MFAP4 has been found to bind with elastin microfibrils and interact directly with fibrillin-1, and then aid in elastic fiber formation. However, the regulations of the human

Indexed as

Base SequenceCarrier ProteinsCells, CulturedElastic TissueElastinExtracellular MatrixExtracellular Matrix ProteinsFibrillin-1FibroblastsGlycoproteinsHumansPromoter Regions, GeneticSpecies SpecificityTATA BoxUbiquinoneVitamin ACarrier Proteinscoenzyme Q10ElastinExtracellular Matrix ProteinsFibrillin-1GlycoproteinsMFAP4 protein, humanUbiquinoneVitamin Aelastic fibersfibroblast cellsmicrofibrillar-associated protein 4 (MFAP4)TATA-less promoter

Identifiers

PMID33182307
PMCPMC7664931
OpenAlexW3101110069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.