Evidence map›Paper›PMID 33181640›Full record

ArticleMedicine2020

Impact of surgical technique and analgesia on clinical outcomes after lung transplantation: A STROBE-compliant cohort study.

Marc Giménez-Milà, Sebastián Videla, Natalia Pallarés, Antoni Sabaté, Jasvir Parmar, Pedro Catarino, Will Tosh, Muhammad Umar Rafiq, Jacinta Nalpon, Kamen Valchanov

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Sternal Complications After Clamshell Surgery for (Heart-)Lung Transplantation-A Systematic Literature Review.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Pooled it
  2. Article
  3. Impact of minimally invasive lung transplantation on early outcomes and analgesia use: A matched cohort study.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Practical considerations for developing a lung transplantation anesthesiology program.Indian journal of thoracic and cardiovascular surgery · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Marc Giménez-MilàDepartment of Anaesthesia and Critical Care, Bellvitge University Hospital, Bellvitge Biomedical.ORCID 0000-0002-3483-7592
Sebastián VidelaClinical Research Support Unit, Clinical Pharmacology Department, Bellvitge University Hospital, Bellvitge Biomedical Research Institute (IDIBELL), University of Barcelona, L'Hospitalet de Llobregat.
Natalia PallarésBiostatistics Unit, Bellvitge Biomedical Research Institute, L'Hospitalet de Llobregat, Barcelona, Spain.
Antoni SabatéDepartment of Anaesthesia and Critical Care, Bellvitge University Hospital, Bellvitge Biomedical.
Jasvir ParmarDepartment of Transplant Medicine.
Pedro CatarinoDepartment of Cardiothoracic Surgery, Royal Papworth Hospital, Cambridge.
Will ToshDepartment of Anaesthesia and Intensive Care, University Hospital Birmingham NHS Foundation Trust, Mindelsohn Way, Birmingham.
Muhammad Umar RafiqDepartment of Cardiothoracic Surgery, Royal Papworth Hospital, Cambridge.
Jacinta NalponPain Specialist Nurse.
Kamen ValchanovDepartment of Anaesthesia and Intensive Care, Royal Papworth Hospital, Cambridge, UK.
Bellvitge University Hospital · ESPapworth Hospital · GBInstitut d'Investigació Biomédica de Bellvitge · ESUniversity Hospitals Birmingham NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is paucity of data on the impact of surgical incision and analgesia on relevant outcomes.A retrospective STROBE-compliant cohort study was performed between July 2007 and August 2017 of patients undergoing lung transplantation. Gender, age, indication for lung transplantation, and the 3 types of surgical access (Thoracotomy (T), Sternotomy (S), and Clamshell (C)) were used, as well as 2 analgesic techniques: epidural and intravenous opioids. Outcome variables were: pain scores; postoperative hemorrhage in the first 24 hours, duration of mechanical ventilation, and length of stay at intensive care unit (ICU).Three hundred forty-one patients were identified. Thoracotomy was associated with higher pain scores than Sternotomy (OR 1.66, 95% CI: 1.01; 2.74, P: .045) and no differences were found between Clamshell and Sternotomy incision. The median blood loss was 800 mL [interquartile range (IQR): 500; 1238], thoracotomy patients had 500 mL [325; 818] (P < .001). Median durations of mechanical ventilation in Thoracotomy, Sternotomy, and Clamshell groups were 19 [11; 37] hours, 34 [IQR 16; 57.5] hours, and 27 [IQR 15; 50.5] hours respectively. Thoracotomy group were discharged earlier from ICU (P < .001).Thoracotomy access produces less postoperative hemorrhage, duration of mechanical ventilation, and lower length of stay in ICU, but higher pain scores and need for epidural analgesia.

Indexed as

Administration, IntravenousAdultAgedAnalgesiaAnalgesia, EpiduralCohort StudiesFemaleHumansKaplan-Meier EstimateLung TransplantationMaleMiddle AgedOutcome Assessment, Health CareProspective StudiesRetrospective StudiesStatistics, Nonparametric

Identifiers

PMID33181640
PMCPMC7668481
OpenAlexW3099039314

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.