Evidence map›Paper›PMID 33181232›Full record

ArticleResuscitation2021

Bougie-assisted endotracheal intubation in the pragmatic airway resuscitation trial.

Austin J Bonnette, Tom P Aufderheide, Jeffrey L Jarvis, Jason A Lesnick, Graham Nichol, Jestin N Carlson, Matthew Hansen, Shannon W Stephens, M Riccardo Colella, Henry E Wang

Abstract readMulticenter Study
In one paragraph

Article in Resuscitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Efficacy of tracheal tube introducers and stylets for endotracheal intubation in the prehospital setting: a systematic review and meta-analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Pooled it
  2. Observational
  3. Observational
  4. Article
  5. Observational
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Austin J BonnetteDepartment of Emergency Medicine, The University of Texas Health Science Center at Houston, Houston, TX, United States.
Tom P AufderheideDepartment of Emergency Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.
Jeffrey L JarvisDepartment of Emergency Medicine, The University of Texas Health Science Center at Houston, Houston, TX, United States; Williamson County Emergency Medical Services, Georgetown, TX, United States.
Jason A LesnickDepartment of Emergency Medicine, The University of Texas Health Science Center at Houston, Houston, TX, United States.
Graham NicholHarborview Center for Prehospital Emergency Care, The University of Washington, Seattle, WA, United States.
Jestin N CarlsonDepartment of Emergency Medicine, The University of Pittsburgh, Pittsburgh, PA, United States.
Matthew HansenDepartment of Emergency Medicine, Oregon Health & Science University, Portland, OR, United States.
Shannon W StephensDepartment of Surgery, The University of Alabama at Birmingham, Birmingham, AL, United States.
M Riccardo ColellaDepartment of Emergency Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.
Henry E WangDepartment of Emergency Medicine, The University of Texas Health Science Center at Houston, Houston, TX, United States. Electronic address: henry.e.wang@uth.tmc.edu.

Funding

Pragmatic Trial of Airway Management in Out-of-Hospital Cardiac ArrestUH3HL125163 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KERBY, JEFFREY D, WANG, HENRY E. · 2015 to 2018
$2.7M
Pragmatic Trial of Airway Management in Out-of-Hospital Cardiac ArrestUH2HL125163 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WANG, HENRY E. · 2014 to 2014
$481k
NHLBI NIH HHS UH2 HL125163NHLBI NIH HHS UH3 HL125163
6 · The paper itself

Abstract

objectiveParamedics may perform endotracheal intubation (ETI) while treating patients with out-of-hospital cardiac arrest (OHCA). The gum elastic Bougie (Bougie) is an intubation adjunct that may optimize intubation success. There are few reports of Bougie-assisted intubation in OHCA nor its association with outcomes. We compared intubation success rates and OHCA outcomes between Bougie-assisted and non-Bougie ETI in the out-of-hospital Pragmatic Airway Resuscitation Trial (PART).

methodsThis was a secondary analysis of patients receiving ETI enrolled in the Pragmatic Airway Resuscitation Trial (PART), a multicenter clinical trial comparing intubation-first vs. laryngeal tube-first strategies of airway management in adult OHCA. The primary exposure was use of Bougie for ETI-assistance. The primary endpoint was first-pass ETI success. Secondary endpoints included overall ETI success, time to successful ETI, return of spontaneous circulation, 72-h survival, hospital survival and hospital survival with favorable neurologic status (Modified Rankin Score ≤3). We analyzed the data using Generalized Estimating Equations and Cox Regression, adjusting for known confounders.

resultsOf the 3004 patients enrolled in PART, 1227 received ETI, including 440 (35.9%) Bougie-assisted and 787 (64.1%) non-Bougie ETIs. First-pass ETI success did not differ between Bougie-assisted and non-Bougie ETI (53.1% vs. 42.8%; adjusted OR 1.12, 95% CI: 0.97-1.39). ETI overall success was slightly higher in the Bougie-assisted group (56.2% vs. 49.1%; adjusted OR 1.19, 95% CI: 1.01-1.32). Time to endotracheal tube placement or abandonment was longer for Bougie-assisted than non-Bougie ETI (median 13 vs. 11 min; adjusted HR 0.63, 95% CI: 0.45-0.90). While survival to hospital discharge was lower for Bougie-assisted than non-Bougie ETI (3.6% vs. 7.5%; adjusted OR 0.94, 95% CI: 0.92-0.96), there were no differences in ROSC, 72-h survival or hospital survival or hospital survival with favorable neurologic status.

conclusionWhile exhibiting slightly higher ETI overall success rates, Bougie-assisted ETI entailed longer airway placement times and potentially lower survival. The role of the Bougie assistance in ETI of OHCA remains unclear.

Indexed as

Cardiopulmonary ResuscitationEmergency Medical ServicesOut-of-Hospital Cardiac ArrestAdultAirway ManagementHumansIntubation, IntratrachealTreatment OutcomeAirway managementCardiopulmonary arrestEmergency medical serviceIntubation

Identifiers

PMID33181232
PMCPMC7855993

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.