Evidence map›Paper›PMID 33181049›Full record

SynthesisJournal of women's health (2002)2021

Brexanolone in Postpartum Depression:

Margaret E Gerbasi, Samantha Meltzer-Brody, Sarah Acaster, Moshe Fridman, Vijayveer Bonthapally, Paul Hodgkins, Stephen J Kanes, Adi Eldar-Lissai

Open access · hybridAbstract readMeta-Analysis
In one paragraph

Synthesis in Journal of women's health (2002), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Margaret E GerbasiSage Therapeutics, Inc., Cambridge, Massachusetts, USA.
Samantha Meltzer-BrodyDepartment of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
Sarah AcasterAcaster Lloyd Consulting Ltd., London, United Kingdom.
Moshe FridmanAMF Consulting, Los Angeles, California, USA.
Vijayveer BonthapallySage Therapeutics, Inc., Cambridge, Massachusetts, USA.
Paul HodgkinsSage Therapeutics, Inc., Cambridge, Massachusetts, USA.
Stephen J KanesSage Therapeutics, Inc., Cambridge, Massachusetts, USA.
Adi Eldar-LissaiSage Therapeutics, Inc., Cambridge, Massachusetts, USA.
Sage Therapeutics (United States) · USLloyd's · GBRED Consulting (Norway) · NOUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

beta-CyclodextrinsDepression, PostpartumAdultClinical Decision-MakingDrug CombinationsFemaleHumansPregnanoloneTreatment Outcomebeta-CyclodextrinsbrexanoloneDrug CombinationsPregnanolonebrexanolonemeaningful changenumber needed to harmnumber needed to treatpostpartum depression

Identifiers

PMID33181049
PMCPMC7957380
OpenAlexW3104603965

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.