Evidence map›Paper›PMID 33180777›Full record

ArticlePloS one2020

First national tuberculosis patient cost survey in Lao People's Democratic Republic: Assessment of the financial burden faced by TB-affected households and the comparisons by drug-resistance and HIV status.

Phonenaly Chittamany, Takuya Yamanaka, Sakhone Suthepmany, Thepphouthone Sorsavanh, Phitsada Siphanthong, Jacques Sebert, Kerri Viney, Thipphasone Vixaysouk, Moeko Nagai, Vilath Seevisay and 3 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

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  8. Effect of Poverty and Rural Settings on Catastrophic Expenditure in Multi-Drug-Resistant Tuberculosis: An Exploratory Study using Propensity Score Matching.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2025
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  20. Post-TB health and wellbeing.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 7 countries.

Phonenaly ChittamanyNational TB Programme, Ministry of Health, Vientiane, Lao PDR.
Takuya YamanakaGlobal Tuberculosis Programme, World Health Organization, Geneva, Switzerland.ORCID 0000-0002-0807-2370
Sakhone SuthepmanyNational TB Programme, Ministry of Health, Vientiane, Lao PDR.
Thepphouthone SorsavanhNational TB Programme, Ministry of Health, Vientiane, Lao PDR.
Phitsada SiphanthongNational TB Programme, Ministry of Health, Vientiane, Lao PDR.
Jacques SebertNational TB Programme, Ministry of Health, Vientiane, Lao PDR.
Kerri VineyGlobal Tuberculosis Programme, World Health Organization, Geneva, Switzerland.
Thipphasone VixaysoukWorld Health Organization, Country Office, Vientiane, Lao PDR.
Moeko NagaiWorld Health Organization, Country Office, Vientiane, Lao PDR.
Vilath SeevisayWorld Health Organization, Country Office, Vientiane, Lao PDR.
Kiyohiko IzumiWorld Health Organization, Country Office, Vientiane, Lao PDR.
Fukushi MorishitaWorld Health Organization, Regional Office for the Western Pacific, Manila, Philippines.
Nobuyuki NishikioriGlobal Tuberculosis Programme, World Health Organization, Geneva, Switzerland.
World Health Organization - Pakistan · PKAustralian National University · AULondon School of Hygiene & Tropical Medicine · GBWorld Health Organization · CHWorld Health Organization Regional Office for the Western Pacific · PH

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundTuberculosis (TB) patients incur large costs for care seeking, diagnosis, and treatment. To understand the magnitude of this financial burden and its main cost drivers, the Lao People's Democratic Republic (PDR) National TB Programme carried out the first national TB patient cost survey in 2018-2019.

methodA facility-based cross-sectional survey was conducted based on a nationally representative sample of TB patients from public health facilities across 12 provinces. A total of 848 TB patients including 30 drug resistant (DR)-TB and 123 TB-HIV coinfected patients were interviewed using a standardised questionnaire developed by the World Health Organization. Information on direct medical, direct non-medical and indirect costs, as well as coping mechanisms was collected. We estimated the percentage of TB-affected households facing catastrophic costs, which was defined as total TB-related costs accounting for more than 20% of annual household income.

resultThe median total cost of TB care was US$ 755 (Interquartile range 351-1,454). The costs were driven by direct non-medical costs (46.6%) and income loss (37.6%). Nutritional supplements accounted for 74.7% of direct non-medical costs. Half of the patients used savings, borrowed money or sold household assets to cope with TB. The proportion of unemployment more than doubled from 16.8% to 35.4% during the TB episode, especially among those working in the informal sector. Of all participants, 62.6% of TB-affected households faced catastrophic costs. This proportion was higher among households with DR-TB (86.7%) and TB-HIV coinfected patients (81.1%).

conclusionIn Lao PDR, TB patients and their households faced a substantial financial burden due to TB, despite the availability of free TB services in public health facilities. As direct non-medical and indirect costs were major cost drivers, providing free TB services is not enough to ease this financial burden. Expansion of existing social protection schemes to accommodate the needs of TB patients is necessary.

Indexed as

AdultCost of IllnessCross-Sectional StudiesEmploymentFamily CharacteristicsFemaleFinancial StressGovernment ProgramsHIV InfectionsHumansIncomeLaosMaleMiddle AgedPublic SectorSocioeconomic Factors

Identifiers

PMID33180777
PMCPMC7660466
OpenAlexW3102981791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.