Evidence map›Paper›PMID 33180358›Full record

ArticleAngewandte Chemie (International ed. in English)2021

Light-Activated Electron Transfer and Catalytic Mechanism of Carnitine Oxidation by Rieske-Type Oxygenase from Human Microbiota.

Muralidharan Shanmugam, Mussa Quareshy, Alexander D Cameron, Timothy D H Bugg, Yin Chen

Open access · hybridAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Muralidharan ShanmugamManchester Institute of Biotechnology (MIB) & Photon Science Institute (PSI), University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK.ORCID 0000-0003-3818-1401
Mussa QuareshySchool of Life Sciences, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK.ORCID 0000-0001-8115-9803
Alexander D CameronSchool of Life Sciences, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK.
Timothy D H BuggDepartment of Chemistry, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK.
Yin ChenSchool of Life Sciences, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK.ORCID 0000-0002-0367-4276
University of Warwick · GBUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidation of quaternary ammonium substrate, carnitine by non-heme iron containing Acinetobacter baumannii (Ab) oxygenase CntA/reductase CntB is implicated in the onset of human cardiovascular disease. Herein, we develop a blue-light (365 nm) activation of NADH coupled to electron paramagnetic resonance (EPR) measurements to study electron transfer from the excited state of NADH to the oxidized, Rieske-type, [2Fe-2S]

Indexed as

LightMicrobiotaAcinetobacter baumanniiBacterial ProteinsCarnitineCatalysisElectron Spin Resonance SpectroscopyElectron TransportHumansIron-Sulfur ProteinsMutagenesis, Site-DirectedNADOxidation-ReductionOxidoreductasesBacterial ProteinsCarnitineIron-Sulfur ProteinsNADOxidoreductasesannealingelectron paramagnetic resonanceiron-sulfur proteinsmetalloenzymesredox enzyme

Identifiers

PMID33180358
PMCPMC7986066
OpenAlexW3103928124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.