Evidence map›Paper›PMID 33180321›Full record

ArticleInfectious diseases and therapy2021

Co-Existence of Carbapenemase-Encoding Genes in Acinetobacter baumannii from Cancer Patients.

Reham Wasfi, Fatma Rasslan, Safaa S Hassan, Hossam M Ashour, Ola A Abd El-Rahman

Abstract read
In one paragraph

Article in Infectious diseases and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Global spread of drug-resistantAnnals of medicine and surgery (2012) · 2026
    Article
  5. Article
  6. Article
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  8. Global genomic epidemiology and plasmid-mediated dissemination ofCurrent research in microbial sciences · 2025
    Article
  9. Article
  10. Phenotypic and Molecular Characterization of Hypervirulent and Multidrug-ResistantThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Article
  11. Article
  12. Antibiotics (Basel, Switzerland) · 2023
    Article
  13. Article
  14. Article
  15. Carbapenemase genes distribution in clonal lineages ofFrontiers in cellular and infection microbiology · 2023
    Article
  16. Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2023
    Review
  17. Article
  18. Article
  19. Molecular Characterization of Carbapenem-ResistantInfection and drug resistance · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Reham WasfiDepartment of Microbiology and Immunology, Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), Giza, Egypt.
Fatma RasslanDepartment of Microbiology and Immunology, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.
Safaa S HassanDepartment of Clinical Pathology, National Cancer Institute, Cairo University, Cairo, Egypt.
Hossam M AshourDepartment of Integrative Biology, College of Arts and Sciences, University of South Florida, St. Petersburg, FL, USA. hossamking@mailcity.com.ORCID http://orcid.org/0000-0002-1256-7368
Ola A Abd El-RahmanDepartment of Microbiology and Immunology, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcinetobacter baumannii is an opportunistic pathogen, which can acquire new resistance genes. Infections by carbapenem-resistant A. baumannii (CRAB) in cancer patients cause high mortality.

methodsCRAB isolates from cancer patients were screened for carbapenemase-encoding genes that belong to Ambler classes (A), (B), and (D), followed by genotypic characterization by enterobacterial-repetitive-Intergenic-consensus-polymerase chain reaction (ERIC-PCR) and multilocus-sequence-typing (MLST).

resultsA total of 94.1% of CRAB isolates co-harbored more than one carbapenemase-encoding gene. The genes bla

conclusionThe findings are alarming and call for measures to prevent and control the spread of MBL-encoding genes among bacteria causing infections in cancer patients and other immunocompromised patient populations.

Indexed as

CancerCarbapenem-resistant Acinetobacter baumannii (CRAB)Metallo-β-lactamase (MBL)Multilocus sequence typing (MLST)

Identifiers

PMID33180321
PMCPMC7954895

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.