Evidence map›Paper›PMID 33180262›Full record

ArticleClinical journal of gastroenterology2021

Huge hepatocellular carcinoma with extrahepatic collateral arteries successfully treated by multidisciplinary treatment including laparoscopic devascularization: a case report.

Kensuke Yamamura, Toru Beppu, Nobutaka Sato, Eri Oda, Koichi Kinoshita, Hideaki Yuki, Toshihiko Motohara, Hideaki Miyamoto, Tsutomu Oda, Shinichi Akahoshi

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In one paragraph

Article in Clinical journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Kensuke YamamuraDepartment of Surgery, Yamaga City Medical Center, 511, Yamaga, Kumamoto, 861-0593, Japan.ORCID http://orcid.org/0000-0003-0506-6394
Toru BeppuDepartment of Surgery, Yamaga City Medical Center, 511, Yamaga, Kumamoto, 861-0593, Japan. tbeppu@yamaga-mc.jp.
Nobutaka SatoDepartment of Surgery, Yamaga City Medical Center, 511, Yamaga, Kumamoto, 861-0593, Japan.
Eri OdaDepartment of Surgery, Yamaga City Medical Center, 511, Yamaga, Kumamoto, 861-0593, Japan.
Koichi KinoshitaDepartment of Surgery, Yamaga City Medical Center, 511, Yamaga, Kumamoto, 861-0593, Japan.
Hideaki YukiDepartment of Radiology, Yamaga City Medical Center, Kumamoto, Japan.
Toshihiko MotoharaDepartment of Gastroenterology, Yamaga City Medical Center, Kumamoto, Japan.
Hideaki MiyamotoDepartment of Medical Oncology, Yamaga City Medical Center, Kumamoto, Japan.
Tsutomu OdaOda Surgical Clinic, Kumamoto, Japan.
Shinichi AkahoshiDepartment of Surgery, Yamaga City Medical Center, 511, Yamaga, Kumamoto, 861-0593, Japan.
Sunagawa City Medical Center · JPKumamoto Orthopedic Surgery Hospital · JPYamagata University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multidisciplinary treatment is recommended for the management of patients with advanced hepatocellular carcinoma (HCC). Some operative decollateralization of extrahepatic feeding arteries with laparotomy have been introduced for HCC. We herein newly develop laparoscopic devascularization (LDEV) to continue transarterial chemoembolization (TACE) for HCC with extrahepatic collateral arteries. A 74-year-old man with multiple huge HCC (4 tumors, 18 cm in diameter) and poor liver function (non-alcoholic steatohepatitis, Child-Pugh score 7) was treated with 6 times of chemoembolization in combination with LDEV, 3 times of ablation therapies, and lenvatinib therapy. His tumor markers were triple positive (AFP, 12,906.5 ng/ml; PIVKA-II, 491,743 mAU/ml; AFP-L3, 91.8%) before treatments; however, they all returned to normal limits. Complete response was achieved according to the modified RECIST criteria. Unfortunately, he died 6 months after the final treatment with no recurrence of HCC due to the postoperative complication of primary lung cancer. LDEV is a useful tool to continue effective TACE, and multidisciplinary treatment including chemoembolization and LDEV can cure advanced HCC patients with extrahepatic collaterals and impaired liver function.

Indexed as

Carcinoma, HepatocellularChemoembolization, TherapeuticLaparoscopyLiver NeoplasmsAgedArteriesHumansMaleNeoplasm Recurrence, LocalRetrospective StudiesTreatment OutcomeCase reportExtrahepatic collateral arteryHepatocellular carcinomaLaparoscopic devascularizationTransarterial chemoembolization

Identifiers

PMID33180262
OpenAlexW3103348756

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.