ReviewCurrent psychiatry reports2020
Understanding Brain Mechanisms of Reactive Aggression.
Review in Current psychiatry reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
49 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The analysis of the prefrontal cortex and its facilitator role of violence: conclusions of a systematic review and meta-analysis based on neuroimaging results.Brain imaging and behavior · 2026Pooled it
- Emotion Regulation and Aggression: A Systematic Review and Meta-Analysis.Aggressive behavior · 2026Pooled it
- Neural correlates of aggression in personality disorders from the perspective of DSM-5 maladaptive traits: a systematic review.Translational psychiatry · 2023Pooled it
- Clarifying the role of Cortico-Cortical and Amygdalo-Cortical brain dysconnectivity associated with Conduct Problems.NeuroImage. Clinical · 2023Pooled it
- Targeting aggression with prefrontal high-definition transcranial direct current stimulation.Scientific reports · 2026Trial
- Oxytocin effects on amygdala reactivity to angry faces in males and females with antisocial personality disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Trial
- Relevance of the negative valence system, the cognitive system, and their interactions for understanding aggression in mental disorders.Der Nervenarzt · 2026Review
- Neuropsychobiological transdiagnostic risk mechanisms for aggression in mental disorders across the life span.BMC psychiatry · 2026Article
- Epidemiology of aggression and violence in mental disorders and the approach of TRR 379.Der Nervenarzt · 2026Review
- Emotion-specific amygdala habituation in treatment-referred young adults with antisocial histories: links with internalizing and externalizing symptoms and future recidivism.Neuroimage. Reports · 2026Article
- Frustrative non-reward: A cross-species probe to study brain mechanisms of irritability.Translational psychiatry · 2026Review
- Parental physiological responses shape how children's emotional reactivity relates to aggression.Scientific reports · 2026Article
- Therapists and ward staff experiences of virtual reality-assisted aggression treatment in a maximum-security forensic psychiatric clinic.BMC psychiatry · 2026Article
- Trait mindfulness and aggressive behavior in physical education undergraduates: a cross-sectional serial mediation analysis of anger rumination and self-control.Frontiers in psychology · 2026Article
- Burned aggression: the relationship between burnout and aggressive behaviour among young adults in Czechia.Frontiers in psychiatry · 2026Article
- Risk and resilience: adverse and positive childhood experiences and aggression in adults with and without ADHD.Frontiers in psychiatry · 2026Article
- Review: Suicide and its relationship to aggression and impulsivity.Cognitive, affective & behavioral neuroscience · 2025Review
- Modulating interhemispheric prefrontal dynamics of aggressive behavior: Sex differences and the association with personal disposition.Cognitive, affective & behavioral neuroscience · 2025Article
- The dark sides of the brain: A systematic review and meta-analysis of functional neuroimaging studies on trait aggressionAggression and violent behavior · 2025Article
- Using Machine Learning to Determine a Functional Classifier of Retaliation and Its Association With Aggression.JAACAP open · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewTo review the current literature on biobehavioral mechanisms involved in reactive aggression in a transdiagnostic approach. RECENT
findingsAggressive reactions are closely related to activations in the brain's threat circuitry. They occur in response to social threat that is experienced as inescapable, which, in turn, facilitates angry approach rather than fearful avoidance. Provocation-induced aggression is strongly associated with anger and deficits in cognitive control including emotion regulation and inhibitory control. Furthermore, the brain's reward system plays a particular role in anger-related, tit-for-tat-like retaliatory aggression in response to frustration. More research is needed to further disentangle specific brain responses to social threat, provocation, and frustration. A better understanding of the psychological and neurobiological mechanisms involved in reactive aggression may pave the way for specific mechanism-based treatments, involving biological or psychotherapeutic approaches or a combination of the two.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.