Evidence map›Paper›PMID 33180174›Full record

ArticlePsychopharmacology2021

No differences in delay discounting between smokers with and without HIV.

Cory Czuczman, Morgan Thompson, E Paul Wileyto, Robert Schnoll, David Metzger, Frank Leone, Karam Mounzer, Robert Gross, Rebecca L Ashare

Registry-linked trialAbstract read
In one paragraph

Article in Psychopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03169101 (Understanding the Role of Cognitive Dysfunction in the Treatment of Nicotine Dependence Among HIV-infected Smokers), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03169101 completednot on this map

Understanding the Role of Cognitive Dysfunction in the Treatment of Nicotine Dependence Among HIV-infected Smokers

TypeobservationalSponsorUniversity of PennsylvaniaRan2016 to 2022Enrolled274ConditionsSmoking CessationArmsNicotine patch, Behavioral counseling
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cory CzuczmanDepartment of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite, Philadelphia, PA, 4100, USA.
Morgan ThompsonDepartment of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite, Philadelphia, PA, 4100, USA.
E Paul WileytoDepartment of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Robert SchnollDepartment of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite, Philadelphia, PA, 4100, USA.
David MetzgerDepartment of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite, Philadelphia, PA, 4100, USA.
Frank LeonePulmonary, Allergy, and Critical Care Division, University of Pennsylvania Presbyterian Medical Center, 51 N. 39th Street, Philadelphia, PA, USA.
Karam MounzerPhiladelphia FIGHT, 1233 Locust St., Philadelphia, PA, USA.
Robert GrossDepartment of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Rebecca L AshareDepartment of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite, Philadelphia, PA, 4100, USA. rlashare@pennmedicine.upenn.edu.ORCID http://orcid.org/0000-0003-4664-009X

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Ronald G Collman · 1999 to 2026
$78.6M
University of Pennsylvania HIV Clinical Trials UnitUM1AI069534 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Ian Frank, PABLO TEBAS · 2012 to 2026
$33.0M
Penn Mental Health AIDS Research CenterP30MH097488 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Karine Dube, Kelly L Jordan-Sciutto · 2013 to 2026
$23.5M
Understanding the Role of Cognitive Dysfunction in the Treatment of Nicotine Dependence among HIV-Infected SmokersR01DA042682 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI ASHARE, REBECCA · 2016 to 2020
$3.3M
NIAID NIH HHS P30 AI045008NIAID NIH HHS UM1 AI069534NIDA NIH HHS R01 DA042682NIDA NIH HHS R01DA042682NIMH NIH HHS P30 MH097488
6 · The paper itself

Abstract

rationalePeople with HIV (PWH) smoke cigarettes at much higher rates than the general population and evidence-based cessation methods are less effective, putting PWH at greater risk for negative health outcomes. It is critical to identify the factors that underlie this health disparity. Delay discounting-the decline in the value of a reward when it is delayed-may explain this disparity.

objectivesThis study aimed to (1) compare delay discounting between adult smokers with HIV and without HIV and (2) evaluate whether acute smoking abstinence disproportionately increases delay discounting among smokers with HIV.

methodsThis sub-study was part of a larger study (NCT03169101) examining predictors of smoking cessation outcomes among smokers with HIV (n = 34) and smokers without HIV (n = 46) at two counterbalanced laboratory sessions (once smoking-as-usual and once following 24-h biochemically confirmed abstinence) then again, after 8 weeks of smoking cessation treatment.

resultsThere were no significant differences in delay discounting rates between HIV status groups (p = 0.49) or within-subject abstinence effects (p = 0.70). However, smokers without HIV exhibited a significant increase in delay discounting following smoking cessation treatment compared to baseline (p = 0.02), whereas the change among smokers with HIV did not reach statistical significance (p = 0.09).

conclusionsThese findings do not support differences in delay discounting as a reason for the lower success rates of HIV+ smokers at quitting. Although delay discounting may not explain the disparity in smoking rates between people with and without HIV, future work should focus on additional correlates of higher smoking rates and lower quit rates among people with HIV.

Indexed as

Delay DiscountingAdultFemaleHIV InfectionsHumansMaleMiddle AgedRewardSmokersSmokingSmoking CessationTobacco Use DisorderAbstinenceDecision-makingDelay discountingHIVSmokingTobacco cessation

Identifiers

PMID33180174
PMCPMC7855959

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.