Evidence map›Paper›PMID 33179872›Full record

ArticleBirth defects research2020

Trends in prevalence and spatiotemporal distribution of gastroschisis in Arkansas, 1998-2015.

Nahed O ELHassan, Sean G Young, Yevgeniya Gokun, Fei Wan, Wendy N Nembhard

Abstract read
In one paragraph

Article in Birth defects research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nahed O ELHassanDepartment of Pediatrics (Neonatology), Arkansas Children's Hospital, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.ORCID 0000-0003-0868-8420
Sean G YoungArkansas Center for Birth Defects Research and Prevention, Little Rock, Arkansas, USA.
Yevgeniya GokunArkansas Center for Birth Defects Research and Prevention, Little Rock, Arkansas, USA.
Fei WanArkansas Center for Birth Defects Research and Prevention, Little Rock, Arkansas, USA.
Wendy N NembhardArkansas Center for Birth Defects Research and Prevention, Little Rock, Arkansas, USA.ORCID 0000-0002-8318-4049

Funding

Centers for Disease Control and Prevention (CDC) National Center for Birth Defects and Developmental Disabilities 5 U01 DD000491NCBDD CDC HHS U01 DD000491NCBDD CDC HHS U01 DD001285NCBDD CDC HHS U01 DD001306
6 · The paper itself

Abstract

backgroundArkansas (AR) had the highest prevalence of gastroschisis in a recent study including 15 U.S. states. Our objective was to evaluate trends in prevalence and the spatiotemporal distribution of gastroschisis in AR.

methodsInfants with gastroschisis, born 1998-2015, were identified from the Arkansas Reproductive Health Monitoring System. Birth record data were used as denominators for calculations. Maternal residence at delivery was geocoded for spatial analyses. Annual prevalence rates (PRs) were calculated. Joinpoint regression analysis was performed to examine trends in gastroschisis and report the annual percent changes (APCs) in PRs. Spatiotemporal analyses identified counties with unusually high PRs of gastroschisis. Poisson regression, including county, year, and county*year indicators, was fit to evaluate the PRs of gastroschisis, while adjusting for county-level maternal variables.

resultsWe identified 401 cases of gastroschisis among 694,459 live births. The overall PR of gastroschisis was 5.8/10,000 live births. The prevalence of gastroschisis had a significant APC of +5.3% (p < .0001) between 1998 and 2012, followed by a nonsignificant yearly average decrease of -17% through 2015 (p = 0.2). The Emerging Hot Spot Analysis and SaTScan identified an overlapping five-county cluster from 2006 to 2013. Poisson regression model, including county (inside vs. outside cluster), time (before vs. after 2006), and county*time indicators, was fit to evaluate the PRs of gastroschisis. The model did not confirm the presence of a spatiotemporal cluster, once it adjusted for county-level maternal characteristics (p = .549).

conclusionClose monitoring of rates of gastroschisis is warranted to determine if the PRs of gastroschisis continue to decline in AR.

Indexed as

GastroschisisArkansasBirth CertificatesFemaleHumansInfantPrevalenceRisk FactorsArkansasgastroschisisprevalencespatialspatiotemporal

Identifiers

PMID33179872
PMCPMC8756334

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.