Evidence map›Paper›PMID 33179816›Full record

ArticleClinical cardiology2021

Cardiac magnetic resonance feature tracking of the right ventricle in convalescent Kawasaki disease in a large single center.

Qiong Yao, Xi-Hong Hu, Li-Li He

Abstract read
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Article in Clinical cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Qiong YaoDepartment of Radiology, Children's Hospital of Fudan University, Shanghai, China.
Xi-Hong HuDepartment of Radiology, Children's Hospital of Fudan University, Shanghai, China.
Li-Li HeDepartment of Ultrasound, Children's Hospital of Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0001-8661-8327

Funding

The National Key Research and Development Program of China 2016YFC1000500
6 · The paper itself

Abstract

backgroundThe changes in right ventricular (RV) contractility of Kawasaki disease (KD) still remain unclear. HYPOTHESIS: We aimed to determine whether RV systolic dysfunction can be detected by cardiac magnetic resonance (CMR) feature tracking and to find its association with coronary artery lesions (aneurysm, thrombosis and stenosis).

methodsPeak systolic myocardial longitudinal, radial and circumferential strain and the strain rate (RVSL, RVSR, RVSC, RVSRL, RVSRR and RVSRC) in the global RV and three levels (basal, middle and apical) were measured in 66 patients with convalescent KD. A total of 20 controls were included. Comparisons were made with controls and among KD subgroups divided with coronary artery lesions.

resultsRVSC (-10.575% vs. -10.760%), RVSL (-18.150% vs. -18.712%) and RVSRC (-0.815/s vs. -0.924/s) were slightly lower in KD group without significant difference. All the strain and strain rate presented lowest in the basal level. In subgroup comparison, lower RVSL and RVSRL were observed in the giant coronary artery aneurysm (CAA) group; RVSR (15.844% vs. 16.897%), RVSRR (1.245/s vs. 1.322/s) and RVSRC (-0.715/s vs. -0.895/s) were lower in thrombosed group; RVSRL (-1.27/s vs. -1.503/s) were lower in stenosis group. All the comparison in subgroups did not reach significant difference. From the analysis of receiver operating characteristic curve, RVSRL had a better ability to identify KD with giant CAA and stenosis. For the identification of thrombosis, RVSRC had a better ability.

conclusionsLower strain and strain rates of RV were detected in convalescent KD. More pronounced in those with persisting coronary artery lesions.

Indexed as

Child, PreschoolFemaleFollow-Up StudiesHeart VentriclesHumansInfantMagnetic Resonance Imaging, CineMaleMucocutaneous Lymph Node SyndromeRetrospective StudiesROC CurveVentricular Dysfunction, RightVentricular Function, Rightcardiac magnetic resonancecoronary artery aneurysmfeature trackingKawasaki diseasemyocardial fibrosisthrombosis

Identifiers

PMID33179816
PMCPMC7803351

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.