Evidence map›Paper›PMID 33179625›Full record

ReviewPathologica2020

Current prognostic and predictive biomarkers for gastrointestinal tumors in clinical practice.

Matteo Fassan, Aldo Scarpa, Andrea Remo, Giovanna De Maglio, Giancarlo Troncone, Antonio Marchetti, Claudio Doglioni, Giuseppe Ingravallo, Giuseppe Perrone, Paola Parente and 2 more

Abstract readReview
In one paragraph

Review in Pathologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Cancers · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
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  13. Concordance of microsatellite instability and mismatch repair status in paired biopsies and surgical specimens of resectable gastroesophageal adenocarcinoma: time for a call to action.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2023
    Article
  14. Article
  15. The ideal reporting ofPathologica · 2023
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Matteo FassanSurgical Pathology Unit, Department of Medicine (DIMED), University of Padua, Italy.
Aldo ScarpaARC-NET Research Centre, University of Verona, Italy.
Andrea RemoPathology Unit, Service Department, ULSS9 "Scaligera", Verona, Italy.
Giovanna De MaglioDepartment of Pathology, University Hospital of Udine, Italy.
Giancarlo TronconeDepartment of Public Health, Federico II University Medical School Naples, Italy.
Antonio MarchettiCenter of Predictive Molecular Medicine, Center for Excellence on Aging and Translational Medicine, University of Chieti-Pescara, Italy.
Claudio DoglioniVita e Salute University, Milan, Italy.
Giuseppe IngravalloDepartment of Emergency and Organ Transplantation, Section of Pathological Anatomy, University of Bari Aldo Moro, Bari, Italy.
Giuseppe PerroneDepartment of Pathology, Campus Bio-Medico University, Rome, Italy.
Paola ParentePathology Unit, Fondazione IRCCS Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy.
Claudio LuchiniDepartment of Diagnostics and Public Health, Section of Pathology, University and Hospital Trust of Verona, Verona, Italy.
Luca MastracciAnatomic Pathology, San Martino IRCCS Hospital,, Genova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pathologist emerged in the personalized medicine era as a central actor in the definition of the most adequate diagnostic and therapeutic algorithms. In the last decade, gastrointestinal oncology has seen a significantly increased clinical request for the integration of novel prognostic and predictive biomarkers in histopathological reports. This request couples with the significant contraction of invasive sampling of the disease, thus conferring to the pathologist the role of governor for both proper pathologic characterization and customized processing of the biospecimens. This overview will focus on the most commonly adopted immunohistochemical and molecular biomarkers in the routine clinical characterization of gastrointestinal neoplasms referring to the most recent published recommendations, guidelines and expert opinions.

Indexed as

Gastrointestinal NeoplasmsBiomarkers, TumorHumansImmunohistochemistryMolecular Targeted TherapyPathology, MolecularPrecision MedicinePrognosisBiomarkers, Tumorimmunohistochemistrymolecular pathologypredictive markersprognostic markerstargeted therapy

Identifiers

PMID33179625
PMCPMC7931577

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.