Evidence map›Paper›PMID 33179613›Full record

ArticlePathologica2020

Primary malignant ossifying fibromyxoid tumour of the bone. A clinicopathologic and molecular report of two cases.

Marta Sbaraglia, Elena Bellan, Marco Gambarotti, Alberto Righi, Lucia Zanatta, Luisa Toffolatti, Angelo P Dei Tos

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Pathologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Marta SbaragliaDepartment of Pathology, Azienda Ospedale Università Padova, Padova, Italy.
Elena BellanDepartment of Medicine, University of Padua School of Medicine, Padova, Italy.
Marco GambarottiUnit of Pathology, Istituto Ortopedico Rizzoli, Bologna, Italy.
Alberto RighiUnit of Pathology, Istituto Ortopedico Rizzoli, Bologna, Italy.
Lucia ZanattaDepartment of Pathology, Azienda ULSS 2 Marca Trevigiana, Treviso, Italy.
Luisa ToffolattiDepartment of Pathology, Azienda ULSS 2 Marca Trevigiana, Treviso, Italy.
Angelo P Dei TosDepartment of Pathology, Azienda Ospedale Università Padova, Padova, Italy.
Azienda ULSS 9 TREVISO · ITIstituto Ortopedico Rizzoli · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo report the exceptional occurrence of ossifying fibromyxoid tumour (OFMT) as a primary bone lesion. OFMT is a rare soft tissue tumour of uncertain differentiation and variable malignant potential, that occurs in adults with a slight male predominance. It is typically located in the subcutis or in the skeletal muscles of the extremities, followed by trunk or head and neck.

methodsTwo cases of OFMT proven to arise from bone are presented. The first is a 65-year old female with a history of rib "osteosarcoma", presenting with an inferior lobe left lung mass. The second is a man with a lytic lesion of the 5th cervical vertebra that recurred shortly after resection. Following H&E and immunohistochemical examination, tumour samples were analysed by NGS and by break-apart FISH to detect rearrangement of the

results

conclusionsThe demonstration of

Indexed as

Bone NeoplasmsFibroma, OssifyingAdultAgedBiomarkers, TumorDNA-Binding ProteinsDNA, NeoplasmFemaleGene RearrangementHigh-Throughput Nucleotide SequencingHumansImmunohistochemistryIn Situ Hybridization, FluorescenceMaleNeoplasm Recurrence, LocalPolycomb-Group ProteinsBiomarkers, TumorDNA-Binding ProteinsDNA, NeoplasmPHF1 protein, humanPolycomb-Group ProteinsTranscription Factorsbone tumoursOFMTPHF1rare tumourssoft tissue tumours

Identifiers

PMID33179613
PMCPMC8183347
OpenAlexW3097432655

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.