Evidence map›Paper›PMID 33179598›Full record

ArticleeLife2020

Systematic identification of

Kaushik Renganaath, Rockie Chong, Laura Day, Sriram Kosuri, Leonid Kruglyak, Frank W Albert

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Mechanisms of regulatory evolution in yeast.Current opinion in genetics & development · 2022
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. eLife · 2021
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Kaushik Renganaath *Department of Genetics, Cell Biology, & Development, University of Minnesota, Minneapolis, United States.ORCID 0000-0003-1010-3604
Rockie Chong *Department of Chemistry & Biochemistry, University of California, Los Angeles, Los Angeles, United States.ORCID 0000-0001-6736-9687
Laura DayDepartment of Human Genetics, University of California, Los Angeles, Los Angeles, United States.
Sriram KosuriDepartment of Chemistry & Biochemistry, University of California, Los Angeles, Los Angeles, United States.ORCID 0000-0002-4661-0600
Leonid KruglyakDepartment of Human Genetics, University of California, Los Angeles, Los Angeles, United States.ORCID 0000-0002-8065-3057
Frank W AlbertDepartment of Genetics, Cell Biology, & Development, University of Minnesota, Minneapolis, United States.ORCID 0000-0002-1380-8063
Howard Hughes Medical Institute · USUniversity of California, Los Angeles · USUniversity of Minnesota · US

Funding

Genomic approaches for dissecting regulatory variationR35GM124676 · NIGMS · UNIVERSITY OF MINNESOTA · PI Frank Wolfgang Albert · 2017 to 2026
$4.6M
Toward comprehensive genetic dissection of complex traits in yeastR01GM102308 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LEONID KRUGLYAK · 2012 to 2026
$3.3M
REVERSE GENOMICS OF REGULATORY ELEMENTS GOVERNING SPLICINGDP2GM114829 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KOSURI, SRIRAM · 2014 to 2014
$2.3M
Howard Hughes Medical InstituteNIGMS NIH HHS DP2 GM114829NIGMS NIH HHS R01 GM102308NIGMS NIH HHS R35 GM124676
6 · The paper itself

Abstract

Sequence variation in regulatory DNA alters gene expression and shapes genetically complex traits. However, the identification of individual, causal regulatory variants is challenging. Here, we used a massively parallel reporter assay to measure the

Indexed as

Crosses, GeneticDNA Barcoding, TaxonomicDNA, FungalGene Expression Regulation, FungalGene LibraryGenetic VariationPromoter Regions, GeneticQuantitative Trait LociSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsDNA, FungalSaccharomyces cerevisiae ProteinseQTLevolutiongene regulationgeneticsgenetic variationgenomicsS. cerevisiae

Identifiers

PMID33179598
PMCPMC7685706
OpenAlexW3100672635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.