Evidence map›Paper›PMID 33179573›Full record

ReviewMultiple sclerosis (Houndmills, Basingstoke, England)2022

The use and quality of reporting of propensity score methods in multiple sclerosis literature: A review.

Mohammad Ehsanul Karim, Fabio Pellegrini, Robert W Platt, Gabrielle Simoneau, Julie Rouette, Carl de Moor

Abstract readReview
In one paragraph

Review in Multiple sclerosis (Houndmills, Basingstoke, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Excess costs of multiple sclerosis: a register-based study in Sweden.The European journal of health economics : HEPAC : health economics in prevention and care · 2023
    Observational
  5. Recommendations for the use of propensity score methods in multiple sclerosis research.Multiple sclerosis (Houndmills, Basingstoke, England) · 2022
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohammad Ehsanul KarimSchool of Population & Public Health, University of British Columbia, Vancouver, BC, Canada/Centre for Health Evaluation and Outcome Sciences, University of British Columbia, Vancouver, BC, Canada.
Fabio PellegriniBiogen International GmbH, Zug, Switzerland.
Robert W PlattDepartment of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada/Centre for Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital, Montreal, QC, Canada.
Gabrielle SimoneauDepartment of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada/Biogen Canada, Mississauga, ON, Canada.ORCID 0000-0001-9310-6274
Julie RouetteDepartment of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada/Centre for Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital, Montreal, QC, Canada.
Carl de MoorBiogen, Cambridge, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPropensity score (PS) analyses are increasingly used in multiple sclerosis (MS) research, largely owing to the greater availability of large observational cohorts and registry databases.

objectiveTo evaluate the use and quality of reporting of PS methods in the recent MS literature.

methodsWe searched the PubMed database for articles published between January 2013 and July 2019. We restricted the search to comparative effectiveness studies of two disease-modifying therapies.

resultsThirty-nine studies were included in the review, with most studies (62%) published within the past 3 years. All studies reported the list of covariates used for the PS model, but only 21% of studies mentioned how those covariates were selected. Most studies used PS matching (72%), followed by PS adjustment (18%), weighting (15%), and stratification (3%), with some overlap. Most studies using matching or weighting reported checking post-PS covariate imbalance (91%), although about 45% of these studies relied on

conclusionsThe quality of reporting of PS methods in the MS literature is sub-optimal in general, and in some cases, inappropriate methods are used.

Indexed as

Multiple SclerosisHumansPropensity Scorecausal inferenceComparative effectivenessdisease-modifying therapiesmultiple sclerosisobservational studypropensity score

Identifiers

PMID33179573
PMCPMC9260477

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.