Evidence map›Paper›PMID 33179402›Full record

ArticleJournal of hepato-biliary-pancreatic sciences2021

A novel hydrogel sheet prevents postoperative pancreatic fistula in a rat model.

Akira Kemmochi, Takafumi Tamura, Yoshio Shimizu, Yohei Owada, Yusuke Ozawa, Katsuji Hisakura, Tatsuya Oda, Yayoi Kawano, Takehisa Hanawa, Nobuhiro Ohkohchi

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Journal of hepato-biliary-pancreatic sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Akira KemmochiDepartment of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.ORCID https://orcid.org/0000-0002-4970-3706
Takafumi TamuraDepartment of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Yoshio ShimizuDepartment of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Yohei OwadaDepartment of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Yusuke OzawaDepartment of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Katsuji HisakuraDepartment of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Tatsuya OdaDepartment of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Yayoi KawanoFaculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Japan.
Takehisa HanawaFaculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Japan.
Nobuhiro OhkohchiDepartment of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
University of Tsukuba · JPTokyo University of Science · JP

Funding

KAKENHI 16K10489KAKENHI 18K08641KAKENHI 26861059
6 · The paper itself

Abstract

aimTo evaluate the efficacy of a novel hydrogel sheet in preventing postoperative pancreatic fistula (POPF).

backgroundPostoperative pancreatic fistula is a life-threatening complication. As no study has reported the use of hydrogel sheets in preventing POPF, their effectiveness for that purpose remains unclear.

methodsA novel hydrogel sheet made of polyvinyl alcohol (PVA) was prepared by the freeze-thaw method. The pancreatic ducts and surrounding pancreatic parenchyma of rats were transected to induce a pancreatic fistula. Next, the sheet was attached to the transection site. Ascitic fluid amylase and lipase concentrations were measured. Neoveil

resultsThe hydrogel sheet remained in place 48 hours postoperatively. The ascitic amylase concentrations in the control, VIEWGEL

conclusionsThis novel hydrogel sheet effectively prevents pancreatic fistulas and has promising clinical application potential.

Indexed as

HydrogelsPancreatic FistulaAmylasesAnimalsPancreasPancreatic DuctsPostoperative ComplicationsRatsAmylasesHydrogelshydrogelpancreatic fistulapolyvinyl alcoholpostoperative pancreatic fistula

Identifiers

PMID33179402
PMCPMC7984228
OpenAlexW3102242765

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.