ArticleJournal of thrombosis and haemostasis : JTH2021
Overall and abdominal obesity in relation to venous thromboembolism.
Article in Journal of thrombosis and haemostasis : JTH, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Metabolic Disorders and Risk of Portal Vein Thrombosis in Liver Cirrhosis: A Systematic Review and Meta-Analysis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2022Pooled it
- Effectiveness of combining Qingyanyin formulated granules with press needles in treating abdominal obesity: a multicenter randomized controlled trial.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2025Trial
- Effect of exercise training with laser phototherapy on homeostasis balance resistant to hypercoagulability in seniors with obesity: a randomized trial.Scientific reports · 2023Trial
- Association of triglyceride-glucose related indices with the incidence of venous thromboembolism: a nationwide prospective cohort study based on the UK Biobank.BMC cardiovascular disorders · 2026Article
- Metabolic syndrome and venous thromboembolism: the role of abdominal obesity and sex differences.Journal of thrombosis and thrombolysis · 2026Article
- Obesity significantly elevates thromboembolism risk in severe trauma, yet essential resuscitation with TXA and erythrocytes remains safe.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Diagnostic Performance of a DOAC Urine Dipstick in Obese Outpatients with Atrial Fibrillation: Comparison with Plasma Concentrations.Journal of clinical medicine · 2026Article
- The association between body mass index and lower extremity deep venous abnormalities identified by computed tomography venography.Frontiers in public health · 2026Article
- Reply to: Use of a Risk Assessment Model for Venous Thromboembolism Is Associated with Decreased Prophylaxis.Journal of general internal medicine · 2026Article
- Risk factors for venous thromboembolism after knee arthroscopy: a systematic review and meta-analysis.Thrombosis journal · 2025Review
- The Interplay Between Obesity and Venous Thromboembolism: From Molecular Aspects to Clinical Issue.International journal of molecular sciences · 2025Review
- Branch Retinal Artery Occlusion in a Young Adult: A Diagnostic Clue to Systemic Embolic Risk.Cureus · 2025Article
- Causal effects of childhood obesity on venous thromboembolism in adulthood: A bidirectional Mendelian randomization study.Medicine · 2025Article
- Metabolic syndrome, adipokines, coagulation factors, and venous thromboembolism: a two-step Mendelian randomization study.Diabetology & metabolic syndrome · 2025Article
- Sedentary behaviors and venous thromboembolism risk among older women: the Objective Physical Activity and Cardiovascular Health study.Journal of thrombosis and haemostasis : JTH · 2025Article
- Postpartum Superior Mesenteric Vein Thrombosis and Heparin-Induced Thrombocytopenia: Clinical Insights.The American journal of case reports · 2025Article
- Advances in Mendelian Randomization Studies of Obesity Over the Past Decade: Uncovering Key Genetic Mechanisms.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Review
- Increased sagittal abdominal diameter is associated with a higher risk of kidney stones.PloS one · 2025Article
- Impact of thyroid function on coagulation and venous thromboembolism: a two-sample mendelian randomization study.Journal of thrombosis and thrombolysis · 2024Article
- Two-sample Mendelian randomization analysis reveals causal relationships between blood lipids and venous thromboembolism.Haematologica · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundAbdominal obesity has been shown to be a superior measure over overall obesity for detecting cardiovascular risk.
objectiveWe conducted this study to compare the effects of overall and abdominal obesity on venous thromboembolism (VTE) and to calculate population attributable fraction for obesity for VTE.
methodsBody mass index (BMI) and waist circumference (WC) were used to represent overall and abdominal obesity, respectively. In the cohort study, we included 74317 Swedish adults with anthropometric measures in 1997 and of whom 4332 were diagnosed with VTE until the end of 2017. A Mendelian randomization study was conducted to investigate causal associations of BMI, WC, and WC adjusted for BMI with VTE using data from FinnGen and UK Biobank study. Population attributable fraction was calculated for overall and abdominal obesity for VTE.
resultsIn the cohort study, there were dose-response associations of BMI and WC with VTE. The association between BMI and VTE was attenuated largely after adjusting for WC. Among individuals with normal BMI, participants with substantially increased WC had 53% higher (hazard ratio 1.53; 95% confidence interval, 1.28, 1.81) risk of VTE compared to those with normal WC. The causality of the association of WC adjusted for BMI with VTE was confirmed in Mendelian randomization analysis. The estimated population-attributable risk due to elevated BMI and WC were 12.4% (8.4%, 16.5%) and 23.7% (18.1%, 29.4%), respectively.
conclusionsWC might be a preferable indicator linking obesity to VTE. A large proportion of VTE cases can be prevented if the population maintained a healthy BMI and WC.
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