SynthesisWorld journal of surgery2021
Outcomes of Laparoscopic Splenectomy for Treatment of Splenomegaly: A Systematic Review and Meta-analysis.
Synthesis in World journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 35 citations in OpenAlex.
- Pediatric laparoscopic splenectomy using a repurposed sterile diathermy pouch as a retrieval bag: preliminary experience.BMC surgery · 2026Article
- Robotic partial splenectomy: a new standardized approach.Surgery today · 2026Article
- Clinical Research Analysis and Application Value of the Laparoscopic Retroperitoneal Approach in In Situ Splenectomy.Gastroenterology research and practice · 2026Article
- Predicting operative complexity in laparoscopic splenectomy: a validated preoperative scoring system.Surgical endoscopy · 2025Article
- SOHO State of the Art Updates and Next Questions | Challenging Scenarios in the Management of Myeloproliferative Neoplasms.Clinical lymphoma, myeloma & leukemia · 2025Review
- Retrospective investigation of patients undergoing splenectomy: Our 8-year clinical experience in a single center.Northern clinics of Istanbul · 2025Article
- Preoperative high-precision three-dimensional reconstruction in laparoscopic splenectomy for supramassive splenomegaly: a case report and literature review.Frontiers in medicine · 2025Article
- Postoperative complications among dialysis-requiring patients undergoing splenectomy.Langenbeck's archives of surgery · 2024Article
- Percutaneous Computed Tomography (CT) Fluoroscopy-Guided Biopsy of the Spleen Using Fibrin Glue as a Sealant.Diagnostics (Basel, Switzerland) · 2024Article
- [Splenic surgery in hematological diseases : Indications and surgical technique].Chirurgie (Heidelberg, Germany) · 2023Review
- Splenic lymphangiomas as a common indication for splenectomy: a case series with literature review.BMC surgery · 2022Review
- Pancreatic Fistula and Biochemical Leak after Splenectomy: Incidence and Risk Factors-A Retrospective Single-Center Analysis.Langenbeck's archives of surgery · 2022Article
- Laparoscopic splenectomy and esophagogastric devascularization combined with fast-track principles offers greater benefit for patients with portal hypertension.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2022Article
- Letter to the Editor: Outcomes of Laparoscopic Splenectomy for Treatment of Splenomegaly: A Systematic Review and Meta-analysis.World journal of surgery · 2021Article
- Author's Reply: Outcomes of Laparoscopic Splenectomy for the treatment of Splenomegaly: A Systematic Review and Meta-analysis.World journal of surgery · 2021Article
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo review the evidence regarding the outcomes of laparoscopic techniques in cases of splenomegaly.
backgroundEndoscopic approaches such as laparoscopic, hand-assisted laparoscopic, and robotic surgery are commonly used for splenectomy, but the advantages in cases of splenomegaly are controversial. REVIEW
methodsWe conducted a systematic review using PRISMA guidelines. PubMed/MEDLINE, ScienceDirect, Scopus, Cochrane Library, and Web of Science were searched up to February 2020.
resultsNineteen studies were included for meta-analysis. In relation to laparoscopic splenectomy (LS) versus open splenectomy (OS), 12 studies revealed a significant reduction in length of hospital stay (LOS) of 3.3 days (p = <0.01) in the LS subgroup. Operative time was higher by 44.4 min (p < 0.01) in the LS group. Blood loss was higher in OS 146.2 cc (p = <0.01). No differences were found regarding morbimortality. The global conversion rate was 19.56%. Five studies compared LS and hand-assisted laparosocpic splenectomy (HALS), but no differences were observed in LOS, blood loss, or complications. HALS had a significantly reduced conversion rate (p < 0.01). In two studies that compared HALS and OS (n = 66), HALS showed a decrease in LOS of 4.5 days (p < 0.01) and increase of 44 min in operative time (p < 0.01), while OS had a significantly higher blood loss of 448 cc (p = 0.01). No differences were found in the complication rate.
conclusionLS is a safe approach for splenomegaly, with clear clinical benefits. HALS has a lower conversion rate. Higher-quality confirmatory trials with standardized splenomegaly grading are needed before definitive recommendations can be provided. Prospero registration number: CRD42019125251.
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