Evidence map›Paper›PMID 33178995›Full record

ArticleAME case reports2020

Acute ischemic stroke as initial manifestation of undiagnosed iron deficiency anemia: case-report and literature review.

Dana Awad, Omar Kousa, Amr Essa, Jason Kuniyoshi, Hamza Kousa, Abdallah Qasim, Venkata Andukuri, Thamer Kassim

Open access · diamondAbstract readCase Reports
In one paragraph

Article in AME case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Dana AwadInternal Medicine Residency, Creighton University, Omaha, NE, USA.
Omar KousaInternal Medicine Residency, Creighton University, Omaha, NE, USA.
Amr EssaInternal Medicine Residency, Creighton University, Omaha, NE, USA.
Jason KuniyoshiMedical Student, Creighton University, Omaha, NE, USA.
Hamza KousaMedical Student, University of Sharjah, Sharjah, United Arab Emirates.
Abdallah QasimInternal Medicine Residency, Creighton University, Omaha, NE, USA.
Venkata AndukuriInternal Medicine, Creighton University, Omaha, NE, USA.
Thamer KassimInternal Medicine, Creighton University, Omaha, NE, USA.
Creighton University · USUniversity of Sharjah · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebrovascular disease is the second leading cause of death in the United States in adults aged 65 years and older and is most commonly caused by atherosclerosis. More so, cryptogenic strokes account for one-third of all ischemic strokes. At the same time, iron deficiency anemia is prevalent worldwide and mostly affects females of childbearing age. Here we report a case of a 42-year-old female who presented with symptoms of acute ischemic stroke and was found to have severe iron deficiency anemia. After prompt investigation of other secondary causes, it was determined that her stroke was likely secondary to her iron deficiency anemia. Upon review of the literature, a few case reports showed an association between iron deficiency anemia and strokes in the adult population, but little evidence exists supporting a direct relationship between the two entities. In this case, we aim to evaluate the complex relationship between iron deficiency anemia and stroke and to define a new potential cause of ischemic stroke, which would have been considered earlier as cryptogenic. However, further studies in the future are warranted to validate our observation.

Indexed as

Cerebrovascular diseasecryptogenic strokeiron deficiency anemia

Identifiers

PMID33178995
PMCPMC7608734
OpenAlexW3039695822

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.