Evidence map›Paper›PMID 33178816›Full record

SynthesisBioMed research international2020

Optical Coherence Tomography Angiography Assessment of the Peripapillary Vessel Density and Structure in Patients with Nonarteritic Anterior Ischemic Optic Neuropathy: A Meta-Analysis.

Ling Ling, Kaibao Ji, Liping Xie, Feifei Gao, Qinglin Zhang, Yiqiao Xing, Wentian Zhou

Open access · hybridAbstract readMeta-Analysis
In one paragraph

Synthesis in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
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  5. Article
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Ling LingAffiliated Eye Hospital of Nanchang University, Nanchang Jiangxi, China.
Kaibao JiDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan Hubei, China.ORCID https://orcid.org/0000-0002-7704-8438
Liping XieDepartment of Ophthalmology, Jiangxi Province Cancer Hospital, Nanchang, Jiangxi, China.
Feifei GaoAffiliated Eye Hospital of Nanchang University, Nanchang Jiangxi, China.
Qinglin ZhangDepartment of Ophthalmology, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, Edong Healthcare Group, Huangshi, China.
Yiqiao XingDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan Hubei, China.
Wentian ZhouAffiliated Eye Hospital of Nanchang University, Nanchang Jiangxi, China.ORCID https://orcid.org/0000-0001-5907-5427
Nanchang University · CNWuhan University · CNHubei Polytechnic University · CNJiangxi Provincial Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis meta-analysis is aimed at assessing the peripapillary vessel density (VD) and structural outcomes using optical coherence tomography angiography (OCTA) in patients with nonarteritic anterior ischemic optic neuropathy (NAION).

methodsA comprehensive search of PubMed, Embase, Cochrane Library, and Web of Science databases for literature comparing VD and structural outcomes in patients with NAION and controls was performed. Mean differences (MDs) and its 95% confidence interval (CI) were calculated for continuous estimates. Review Manager (V5.30) was used for analysis.

resultsFourteen published studies met the requirement. The radial peripapillary capillary (RPC) whole enface VD measured by OCTA was significantly lower in patients with NAION compared to that of the controls (MD = -10.51,

conclusionsThe findings suggested that the peripapillary VD and RNFL thickness were attenuated, and the macular GCC thickness was reduced in patients with NAION. OCTA, in the future, may facilitate the diagnosis and monitoring of patients with NAION.

Indexed as

Fluorescein AngiographyTomography, Optical CoherenceAgedCapillariesCase-Control StudiesFemaleHumansMacula LuteaMaleMiddle AgedOptic Neuropathy, IschemicPublication BiasRetinal Ganglion CellsRetinal Vessels

Identifiers

PMID33178816
PMCPMC7647740
OpenAlexW3096463394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.