Evidence map›Paper›PMID 33178751›Full record

ArticleAnnals of translational medicine2020

A better method for the dynamic, precise estimating of blood/haemoglobin loss based on deep learning of artificial intelligence.

Yu-Jie Li, Li-Ge Zhang, Hong-Yu Zhi, Kun-Hua Zhong, Wen-Quan He, Yang Chen, Zhi-Yong Yang, Lin Chen, Xue-Hong Bai, Xiao-Lin Qin and 9 more

Abstract read
In one paragraph

Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yu-Jie LiDepartment of Anaesthesiology, Southwest Hospital, Third Military Medical University (First Affiliated Hospital of Army Medical University), Chongqing, China.
Li-Ge ZhangLaboratory for Automated Reasoning and Programming, Chengdu Institute of Computer Applications, Chinese Academy of Sciences, Chengdu, China.
Hong-Yu ZhiDepartment of Anaesthesiology, Southwest Hospital, Third Military Medical University (First Affiliated Hospital of Army Medical University), Chongqing, China.
Kun-Hua ZhongChongqing Institute of Green and Intelligent Technology, Chinese Academy of Science, Chongqing, China.
Wen-Quan HeDepartment of Anaesthesiology, Southwest Hospital, Third Military Medical University (First Affiliated Hospital of Army Medical University), Chongqing, China.
Yang ChenDepartment of Anaesthesiology, Southwest Hospital, Third Military Medical University (First Affiliated Hospital of Army Medical University), Chongqing, China.
Zhi-Yong YangDepartment of Anaesthesiology, Southwest Hospital, Third Military Medical University (First Affiliated Hospital of Army Medical University), Chongqing, China.
Lin ChenDepartment of Anaesthesiology, Southwest Hospital, Third Military Medical University (First Affiliated Hospital of Army Medical University), Chongqing, China.
Xue-Hong BaiDepartment of Anaesthesiology, Southwest Hospital, Third Military Medical University (First Affiliated Hospital of Army Medical University), Chongqing, China.
Xiao-Lin QinLaboratory for Automated Reasoning and Programming, Chengdu Institute of Computer Applications, Chinese Academy of Sciences, Chengdu, China.
Dan-Feng LiDepartment of Anaesthesiology, Southwest Hospital, Third Military Medical University (First Affiliated Hospital of Army Medical University), Chongqing, China.
Dan-Dan WangDepartment of Anaesthesiology, Southwest Hospital, Third Military Medical University (First Affiliated Hospital of Army Medical University), Chongqing, China.
Jian-Teng GuDepartment of Anaesthesiology, Southwest Hospital, Third Military Medical University (First Affiliated Hospital of Army Medical University), Chongqing, China.
Jiao-Lin NingDepartment of Anaesthesiology, Southwest Hospital, Third Military Medical University (First Affiliated Hospital of Army Medical University), Chongqing, China.
Kai-Zhi LuDepartment of Anaesthesiology, Southwest Hospital, Third Military Medical University (First Affiliated Hospital of Army Medical University), Chongqing, China.
Ju ZhangChongqing Institute of Green and Intelligent Technology, Chinese Academy of Science, Chongqing, China.
Zheng-Yuan XiaDepartment of Anaesthesiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Yu-Wen ChenChongqing Institute of Green and Intelligent Technology, Chinese Academy of Science, Chongqing, China.
Bin YiDepartment of Anaesthesiology, Southwest Hospital, Third Military Medical University (First Affiliated Hospital of Army Medical University), Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDynamic and precise estimation of blood loss (EBL) is quite important for perioperative management. To date, the Triton System, based on feature extraction technology (FET), has been applied to estimate intra-operative haemoglobin (Hb) loss but is unable to directly assess the amount of blood loss. We aimed to develop a method for the dynamic and precise EBL and estimate Hb loss (EHL) based on artificial intelligence (AI).

methodsWe collected surgical patients' non-recycled blood to generate blood-soaked sponges at a set gradient of volume. After image acquisition and preprocessing, FET and densely connected convolutional networks (DenseNet) were applied for EBL and EHL. The accuracy was evaluated using R2, the mean absolute error (MAE), the mean square error (MSE), and the Bland-Altman analysis.

resultsFor EBL, the R2, MAE and MSE for the method based on DenseNet were 0.966 (95% CI: 0.962-0.971), 0.186 (95% CI: 0.167-0.207) and 0.096 (95% CI: 0.084-0.109), respectively. For EHL, the R2, MAE and MSE for the method based on DenseNet were 0.941 (95% CI: 0.934-0.948), 0.325 (95% CI: 0.293-0.355) and 0.284 (95% CI: 0.251-0.317), respectively. The accuracies of EBL and EHL based on DenseNet were more satisfactory than that of FET. Bland-Altman analysis revealed a bias of 0.02 ml with narrow limits of agreement (LOA) (-0.47 to 0.52 mL) and of 0.05 g with narrow LOA (-0.87 to 0.97 g) between the methods based on DenseNet and actual blood loss and Hb loss.

conclusionsWe developed a simpler and more accurate AI-based method for EBL and EHL, which may be more fit for surgeries primarily using sponges and with a small to medium amount of blood loss.

Indexed as

densely connected convolutional networksfeature extraction technologyIntra-operative blood lossintra-operative haemoglobin loss

Identifiers

PMID33178751
PMCPMC7607084

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.