Evidence map›Paper›PMID 33178748›Full record

ArticleAnnals of translational medicine2020

Qualitative and quantitative assessment of pendelluft: a simple method based on electrical impedance tomography.

Ling Sang, Zhanqi Zhao, Po-Jen Yun, Inéz Frerichs, Knut Möller, Feng Fu, Xiaoqing Liu, Nanshan Zhong, Yimin Li

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06494215 (Comparison of Different Methods to Calculate Pendelluft by Electrical Impedance Tomography in Patients Undergoing Invasive Mechanical Ventilation Under Pressure Support Mode), which is not on this map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06494215 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Comparison of Different Methods to Calculate Pendelluft by Electrical Impedance Tomography in Patients Undergoing Invasive Mechanical Ventilation Under Pressure Support Mode

TypeinterventionalSponsorUniversity of Sao Paulo General HospitalRan2024 to 2025Enrolled15ConditionsAsynchrony, Patient-Ventilator, ARDS, Respiratory Insufficiency, Respiratory Effort-Related Arousal &#X7CArmsPressure Support Variation and Calculation of Respiratory Mechanics
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 53 citations in OpenAlex.

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  17. The Proper Assessment of Pendelluft and Absolute End-Expiratory Lung Volume.American journal of respiratory and critical care medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Ling SangDepartment of Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, State Key Lab of Respiratory Diseases, Guangzhou Institute of Respiratory Health, Guangzhou, China.
Zhanqi ZhaoDepartment of Biomedical Engineering, Fourth Military Medical University, Xi'an, China.
Po-Jen YunDivision of Thoracic Surgery, Department of Surgery, Tri-Service General Hospital, Taipei.
Inéz FrerichsDepartment of Anesthesiology and Intensive Care Medicine, University Medical Center of Schleswig-Holstein Campus Kiel, Kiel, Germany.
Knut MöllerInstitute of Technical Medicine, Furtwangen University, Villingen-Schwenningen, Germany.
Feng FuDepartment of Biomedical Engineering, Fourth Military Medical University, Xi'an, China.
Xiaoqing LiuDepartment of Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, State Key Lab of Respiratory Diseases, Guangzhou Institute of Respiratory Health, Guangzhou, China.
Nanshan ZhongDepartment of Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, State Key Lab of Respiratory Diseases, Guangzhou Institute of Respiratory Health, Guangzhou, China.
Yimin LiDepartment of Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, State Key Lab of Respiratory Diseases, Guangzhou Institute of Respiratory Health, Guangzhou, China.
First Affiliated Hospital of Guangzhou Medical University · CNFurtwangen University · DEGuangzhou Medical University · CNAir Force Medical University · CNTri-Service General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPendelluft, defined as asynchronous alveolar ventilation, is caused by different regional time constants or dynamic pleural pressure variations. The aim of the present study was to propose a simple method to evaluate pendelluft based on electrical impedance tomography (EIT). The efficacy of this method was demonstrated in well-known pendelluft scenarios in 6 patients.

methodsTwo patients with flail chest after accidents, two patients with acute respiratory distress syndrome (ARDS) and two patients with acutely exacerbated obstructive lung disease were prospectively included. EIT measurements were performed before and after surgery (in patients with flail chest, who had video-assisted thoracoscopic surgery with ribs fixation), or at two different levels of positive end-expiratory pressure (PEEP; ARDS patients), or two different time points (obstructive lung disease). Pendelluft was assessed by regional phase shift (defined as time difference between global and regional impedance-time curves) and amplitude differences (defined as the impedance difference between sum of all regional tidal variation and the global tidal variation).

resultsIn patients with flail chest, pendelluft diminished several days after surgery (pendelluft amplitude normalized to tidal impedance variation reduced from 88% to 2% in one patient, 12% to 2% in the other). Increased PEEP reduced the amplitude of pendelluft (from 3% to 0% in one patient, 20% to 2% in the other) but not necessarily the phase shifts (average time differences were <0.1 second for both patients for both ins- and expiration) in ARDS patients. Pendelluft assessment in obstructive lung diseases reflected the change in airway resistance (from 5% to 1% in one patient after broncholytic medication administration, as airway resistance fell from 15 to 11 cmH

conclusionsThe proposed EIT-based method can be used to evaluate the degree of pendelluft in dimension of phase shift and amplitude difference.

Indexed as

acute respiratory distress syndrome (ARDS)Electrical impedance tomography (EIT)flail chestobstructive lung diseasependelluft

Identifiers

PMID33178748
PMCPMC7607126
OpenAlexW3086445679

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.