Evidence map›Paper›PMID 33178701›Full record

ArticleFrontiers in cell and developmental biology2020

Effect of Cell Spreading on Rosette Formation by Human Pluripotent Stem Cell-Derived Neural Progenitor Cells.

Ryan F Townshend, Yue Shao, Sicong Wang, Chari L Cortez, Sajedeh Nasr Esfahani, Jason R Spence, K Sue O'Shea, Jianping Fu, Deborah L Gumucio, Kenichiro Taniguchi

Abstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  12. Loss of symmetric cell division of apical neural progenitors drivesmedRxiv : the preprint server for health sciences · 2024
    Article
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  19. Human epiblast lumenogenesis: From a cell aggregate to a lumenal cyst.Seminars in cell & developmental biology · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ryan F TownshendDepartment of Cell & Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, United States.
Yue ShaoDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI, United States.
Sicong WangDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI, United States.
Chari L CortezDepartment of Cell & Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, United States.
Sajedeh Nasr EsfahaniDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI, United States.
Jason R SpenceDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, United States.
K Sue O'SheaDepartment of Cell & Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, United States.
Jianping FuDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI, United States.
Deborah L GumucioDepartment of Cell & Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, United States.
Kenichiro TaniguchiDepartment of Cell & Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, United States.

Funding

TRAINING PROGRAM IN ORGANOGENESIST32HD007505 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PASCA DI MAGLIANO, MARINA, SPENCE, JASON · 1997 to 2021
$6.9M
Morphogenesis of the fetal intestinal epitheliumR01DK089933 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GUMUCIO, DEBORAH L. · 2011 to 2019
$3.6M
NICHD NIH HHS T32 HD007505NIDDK NIH HHS R01 DK089933
6 · The paper itself

Abstract

Neural rosettes (NPC rosettes) are radially arranged groups of cells surrounding a central lumen that arise stochastically in monolayer cultures of human pluripotent stem cell (hPSC)-derived neural progenitor cells (NPC). Since NPC rosette formation is thought to mimic cell behavior in the early neural tube, these rosettes represent important

Indexed as

actin cytoskeletal networkcell spreadinghuman pluripotent stem cellsmicrocontact printingneural progenitor cellsneural rosetteneural tubeRhoA

Identifiers

PMID33178701
PMCPMC7593581

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.