ArticleFrontiers in bioengineering and biotechnology2020
Process Characterization by Definitive Screening Design Approach on DNA Vaccine Production.
Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 8 citations in OpenAlex.
- Lifecycle DoE-The Companion for a Holistic Development Process.Bioengineering (Basel, Switzerland) · 2024Article
- Optimization of an Ultra-Sonication Extraction Method for Major Compounds Found inMolecules (Basel, Switzerland) · 2022Article
- Toward QbD Process Understanding on DNA Vaccine Purification Using Design of Experiment.Frontiers in bioengineering and biotechnology · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plasmid DNA is a vital biological tool for molecular cloning and transgene expression of recombinant proteins; however, decades ago, it has become an exceptionally appealing as a potential biopharmaceutical product as genetic immunization for animal and human use. The demand for large-quantity production of DNA vaccines also increases. Thus, we, herein, presented a systematic approach for process characterization of fed-batch
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Registered trials
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