Evidence map›Paper›PMID 33178669›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Utility of Air Bladder-Derived Nanostructured ECM for Tissue Regeneration.

Jianwei Wang, Jiayu Chen, Yongfeng Ran, Qianhong He, Tao Jiang, Weixu Li, Xiaohua Yu

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. PEDOT-Integrated Fish Swim Bladders as Conductive Nerve Conduits.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  3. Acellular fish skin for wound healing.International wound journal · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jianwei WangDepartment of Orthopedics, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang, China.
Jiayu ChenHangzhou Huamai Medical Devices Co., Ltd., Hangzhou, China.
Yongfeng RanHangzhou Huamai Medical Devices Co., Ltd., Hangzhou, China.
Qianhong HeHangzhou Huamai Medical Devices Co., Ltd., Hangzhou, China.
Tao JiangHangzhou Huamai Medical Devices Co., Ltd., Hangzhou, China.
Weixu LiDepartment of Orthopedics, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang, China.
Xiaohua YuDepartment of Orthopedics, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exploration for ideal bone regeneration materials still remains a hot research topic due to the unmet clinical challenge of large bone defect healing. Bone grafting materials have gradually evolved from single component to multiple-component composite, but their functions during bone healing still only regulate one or two biological processes. Therefore, there is an urgent need to develop novel materials with more complex composition, which convey multiple biological functions during bone regeneration. Here, we report an naturally nanostructured ECM based composite scaffold derived from fish air bladder and combined with dicalcium phosphate (DCP) microparticles to form a new type of bone grafting material. The DCP/acellular tissue matrix (DCP/ATM) scaffold demonstrated porous structure with porosity over 65% and great capability of absorbing water and other biologics.

Indexed as

bone defectbone graftcomposite scaffoldECMosteogenic

Identifiers

PMID33178669
PMCPMC7594528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.