Evidence map›Paper›PMID 33178548›Full record

ArticleBeilstein journal of nanotechnology2020

Selective detection of complex gas mixtures using point contacts: concept, method and tools.

Alexander P Pospelov, Victor I Belan, Dmytro O Harbuz, Volodymyr L Vakula, Lyudmila V Kamarchuk, Yuliya V Volkova, Gennadii V Kamarchuk

Open access · diamondAbstract read
In one paragraph

Article in Beilstein journal of nanotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Alexander P PospelovDepartment of Physical Chemistry, National Technical University "Kharkiv Polytechnic Institute", 2 Kyrpychov Str., Kharkiv, 61002, Ukraine.
Victor I BelanDepartment of Spectroscopy of Molecular Systems and Nanostructured Materials, B. Verkin Institute for Low Temperature Physics and Engineering, 47 Nauky Ave., Kharkiv, 61103, Ukraine.ORCID https://orcid.org/0000-0002-8356-9985
Dmytro O HarbuzDepartment of Physical Chemistry, National Technical University "Kharkiv Polytechnic Institute", 2 Kyrpychov Str., Kharkiv, 61002, Ukraine.
Volodymyr L VakulaDepartment of Spectroscopy of Molecular Systems and Nanostructured Materials, B. Verkin Institute for Low Temperature Physics and Engineering, 47 Nauky Ave., Kharkiv, 61103, Ukraine.ORCID https://orcid.org/0000-0002-3423-9779
Lyudmila V KamarchukDepartment of Pediatrics and Rehabilitation, SI "Institute for Children and Adolescents Health Care" of NAMS of Ukraine, 52-A Yuvileinyi Ave., Kharkiv, 61153, Ukraine.
Yuliya V VolkovaLaboratory of Age Endocrinology and Metabolism, SI "Institute for Children and Adolescents Health Care" of NAMS of Ukraine, 52-A Yuvileinyi Ave., Kharkiv, 61153, Ukraine.
Gennadii V KamarchukDepartment of Spectroscopy of Molecular Systems and Nanostructured Materials, B. Verkin Institute for Low Temperature Physics and Engineering, 47 Nauky Ave., Kharkiv, 61103, Ukraine.ORCID https://orcid.org/0000-0002-1105-8019
B. Verkin Institute for Low Temperature Physics and Engineering of the National Academy of Sciences of Ukraine · UAState Institution "Institute for Children and Adolescents Health Care at the National Academy of Medical Sciences of Ukraine" · UANational Technical University "Kharkiv Polytechnic Institute" · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Of all modern nanosensors using the principle of measuring variations in electric conductance, point-contact sensors stand out in having a number of original sensor properties not manifested by their analogues. The nontrivial nature of point-contact sensors is based on the unique properties of Yanson point contacts used as the sensing elements. The quantum properties of Yanson point contacts enable the solution of some of the problems that could not be solved using conventional sensors measuring conductance. In the present paper, we demonstrate this by showing the potential of quantum point-contact sensors to selectively detect components of a gas mixture in real time. To demonstrate the high efficiency of the proposed approach, we analyze the human breath, which is the most complex of the currently known natural gas mixtures with extremely low concentrations of its components. Point-contact sensors allow us to obtain a spectroscopic profile of the mixture. This profile contains information about the complete set of energy interactions occurring in the point contact/breath system when the breath constituents adsorb to and desorb from the surface of the point-contact conduction channel. With this information we can unambiguously characterize the analyzed system, since knowing the energy parameters is key to successfully identifying and modeling the physicochemical properties of various quantum objects. Using the point-contact spectroscopic profile of a complex gas mixture it is possible to get a functional dependence of the concentration of particular breath components on the amplitude of the sensor output signal. To demonstrate the feasibility of the proposed approach, we analyze the point-contact profiles from the breath of several patients and compare them with the concentrations of serotonin and cortisol in the body of each patient. The obtained results demonstrate that the proposed methodology allows one to get an effective calibration function for a non-invasive analysis of the level of serotonin and cortisol in the human body using the point-contact breath test. The present study indicates some necessary prerequisites for the design of fast detection methods using differential sensor analysis in real time, which can be implemented in various areas of science and technology, among which medicine is one of the most important.

Indexed as

breath profilecortisolhormone detectionpoint contactquantum sensorselective detectionserotoninYanson point contacts

Identifiers

PMID33178548
PMCPMC7607434
OpenAlexW3097544956

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.