Evidence map›Paper›PMID 33178437›Full record

ArticleVeterinary record open2020

Efficacy of oral

Fernando Mosquera Jaramillo, Diego Darley Velasquez Piñeros, Rodrigo Romero Corrêa, Fabio Celidonio Pogliani, Bruno Cogliati, Raquel Yvonne Arantes Baccarin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary record open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Fernando Mosquera JaramilloDepartamento de Clínica Médica, Universidade de São Paulo Faculdade de Medicina Veterinária e Zootecnia, Sao Paulo, Brazil.
Diego Darley Velasquez PiñerosDepartamento de Cirurgia, Universidade de São Paulo Faculdade de Medicina Veterinária e Zootecnia, Sao Paulo, Brazil.
Rodrigo Romero CorrêaDepartamento de Cirurgia, Universidade de São Paulo Faculdade de Medicina Veterinária e Zootecnia, Sao Paulo, Brazil.
Fabio Celidonio PoglianiDepartamento de Clínica Médica, Universidade de São Paulo Faculdade de Medicina Veterinária e Zootecnia, Sao Paulo, Brazil.
Bruno CogliatiDepartamento de Patologia, Universidade de São Paulo Faculdade de Medicina Veterinária e Zootecnia, Sao Paulo, Brazil.
Raquel Yvonne Arantes BaccarinDepartamento de Clínica Médica, Universidade de São Paulo Faculdade de Medicina Veterinária e Zootecnia, Sao Paulo, Brazil.ORCID 0000-0001-9730-0840
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite hepatotoxic effects, imidocarb dipropionate is the drug of choice for treatment of equine piroplasmosis. It is important, therefore, to identify adjuvant therapies that may improve the safety of imidocarb dipropionate by reducing the risk of liver damage during its use. The aim of the present study was to evaluate the hepatoprotective and hepatoregulatory effects of treatment with

methodsTen healthy horses, seroconverted to

resultsAll haematological values remained within normal range for the study population. Histological analysis revealed that treated group animals had 62 per cent less lobular inflammation, 55 per cent less pigment accumulation, 65 per cent less steatosis and 57 per cent less portal inflammation than control group animals, with an equivalent percentage of hydropic degeneration.

conclusion

Indexed as

artichokebiopsyhorseslivermilk thistle

Identifiers

PMID33178437
PMCPMC7646365
OpenAlexW3094735774

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.