Evidence map›Paper›PMID 33178391›Full record

ReviewWorld journal of stem cells2020

Inflammatory bowel disease: Therapeutic limitations and prospective of the stem cell therapy.

Rangnath Mishra, Punita Dhawan, Anand S Srivastava, Amar B Singh

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of stem cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Chemical Profile and In Vitro Protective Effects ofPlants (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Article
  9. Pharmacological Potential ofCurrent issues in molecular biology · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Ulceroprotective Effects ofCurrent issues in molecular biology · 2025
    Article
  14. Toxicology reports · 2025
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Exploring the bioactive properties and mechanism ofAmerican journal of translational research · 2025
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rangnath MishraGlobal Institute of Stem Cell Therapy and Research, San Diego, CA 92122, United States.
Punita DhawanDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68118, United States.
Anand S SrivastavaGlobal Institute of Stem Cell Therapy and Research, San Diego, CA 92122, United States.
Amar B SinghDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68118, United States.
Global Policy Institute · USNebraska Medical Center · US

Funding

Chloroquine-based polymer particles as oral non-absorbable treatment of inflammatory bowel diseaseR01DK124095 · NIDDK · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI OUPICKY, DAVID, SINGH, AMAR B · 2020 to 2023
$2.1M
Mastl, a novel therapeutic target in Colon CancerR21CA216746 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI DHAWAN, PUNITA · 2018 to 2019
$358k
Role of Claudin-2 in Colon TumorigenesisI01BX002761 · VA · OMAHA VA MEDICAL CENTER · PI SINGH, AMAR B · 2016 to 2023
–
BLRD VA I01 BX002086BLRD VA I01 BX002761NCI NIH HHS R21 CA216746NIDDK NIH HHS R01 DK124095
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD), consisting primarily of ulcerative colitis and Crohn's disease, is a group of debilitating auto-immune disorders, which also increases the risk of colitis-associated cancer. However, due to the chronic nature of the disease and inconsistent treatment outcomes of current anti-IBD drugs (

Indexed as

Crohn′s diseaseHematopoietic stem cellsMesenchymal stem cellsMucosal healingUlcerative colitis

Identifiers

PMID33178391
PMCPMC7596447
OpenAlexW3096642971

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.