Intradermal Tranexamic Acid Injection for the Treatment of Melasma: A Pilot Study with 48-week Follow-up.

Suparuj Lueangarun, Punyaphat Sirithanabadeekul, Prapalpitch Wongwicharn, Chutimon Namboonlue, Sarun Pacharapakornpong, Premjit Juntongjin, Therdpong Tempark

Open access · greenAbstract read

PubMed Full text at PMC

In one paragraph

Article in The Journal of clinical and aesthetic dermatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it

0cells of the map it votes in

6citing papers in PubMed

1.4field-weighted citation impact, top 16% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

The effect of topical tranexamic acid with micro-needling and micro-needling alone in treatment of macular amyloidosis.Journal of cosmetic dermatology · 2024
Trial
Clinical Safety and Efficacy of Hyaluronic Acid-Niacinamide-Tranexamic Acid Injectable Hydrogel for Multifactorial Facial Skin Quality Enhancement with Dark Skin Lightening.Gels (Basel, Switzerland) · 2025
Article
Melasma: A Step-by-Step Approach Towards a Multimodal Combination Therapy.Clinical, cosmetic and investigational dermatology · 2024
Review
Efficacy and Safety of Topical Tranexamic Acid Alone or in Combination with Either Fractional Carbon Dioxide Laser or Microneedling for the Treatment of Melasma.Dermatology practical & conceptual · 2023
Article
Understanding Melasma-How Can Pharmacology and Cosmetology Procedures and Prevention Help to Achieve Optimal Treatment Results? A Narrative Review.International journal of environmental research and public health · 2022
Review
Efficacy of Tranexamic acid Microneedling versus Intradermal Injection of Tranexamic Acid in the Treatment of Melasma - A Randomised Controlled Trial.Indian journal of dermatology
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Suparuj LueangarunDrs. Lueangarun, Sirithanabadeekul, Wongwicharn, Namboonlue, Pacharapakornpong, and Juntongjin are with the Division of Dermatology at the Chulabhorn International College of Medicine of Thammasat University in Pathumthani, Thailand.

Punyaphat SirithanabadeekulDrs. Lueangarun, Sirithanabadeekul, Wongwicharn, Namboonlue, Pacharapakornpong, and Juntongjin are with the Division of Dermatology at the Chulabhorn International College of Medicine of Thammasat University in Pathumthani, Thailand.

Prapalpitch WongwicharnDrs. Lueangarun, Sirithanabadeekul, Wongwicharn, Namboonlue, Pacharapakornpong, and Juntongjin are with the Division of Dermatology at the Chulabhorn International College of Medicine of Thammasat University in Pathumthani, Thailand.

Chutimon NamboonlueDrs. Lueangarun, Sirithanabadeekul, Wongwicharn, Namboonlue, Pacharapakornpong, and Juntongjin are with the Division of Dermatology at the Chulabhorn International College of Medicine of Thammasat University in Pathumthani, Thailand.

Sarun PacharapakornpongDrs. Lueangarun, Sirithanabadeekul, Wongwicharn, Namboonlue, Pacharapakornpong, and Juntongjin are with the Division of Dermatology at the Chulabhorn International College of Medicine of Thammasat University in Pathumthani, Thailand.

Premjit JuntongjinDrs. Lueangarun, Sirithanabadeekul, Wongwicharn, Namboonlue, Pacharapakornpong, and Juntongjin are with the Division of Dermatology at the Chulabhorn International College of Medicine of Thammasat University in Pathumthani, Thailand.

Therdpong TemparkDrs. Lueangarun, Sirithanabadeekul, Wongwicharn, Namboonlue, Pacharapakornpong, and Juntongjin are with the Division of Dermatology at the Chulabhorn International College of Medicine of Thammasat University in Pathumthani, Thailand.

Thammasat University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

intradermal microinjectionMelasmamelasma pathogenesismelasma treatmenttranexamic acid

Identifiers

PMID33178380

PMCPMC7595366

OpenAlexW3098349099

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.