Evidence map›Paper›PMID 33178355›Full record

ArticleBeilstein journal of organic chemistry2020

A consensus-based and readable extension of

Benjamin P Kellman, Yujie Zhang, Emma Logomasini, Eric Meinhardt, Karla P Godinez-Macias, Austin W T Chiang, James T Sorrentino, Chenguang Liang, Bokan Bao, Yusen Zhou and 10 more

Abstract read
In one paragraph

Article in Beilstein journal of organic chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. In silico simulation of glycosylation and related pathways.Analytical and bioanalytical chemistry · 2024
    Review
  2. Article
  3. Article
  4. Article
  5. Functions of Glycosylation and Related Web Resources for Its Prediction.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  6. Review
  7. GlycoBioinformatics.Beilstein journal of organic chemistry · 2021
    Article
  8. Simulating the enzymes of ganglioside biosynthesis with Glycologue.Beilstein journal of organic chemistry · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Benjamin P Kellman *See end of main text.ORCID https://orcid.org/0000-0002-0780-6096
Yujie Zhang *See end of main text.ORCID https://orcid.org/0000-0002-1017-0316
Emma LogomasiniSee end of main text.
Eric MeinhardtSee end of main text.
Karla P Godinez-MaciasSee end of main text.
Austin W T ChiangSee end of main text.
James T SorrentinoSee end of main text.
Chenguang LiangSee end of main text.
Bokan BaoSee end of main text.
Yusen ZhouSee end of main text.
Sachiko AkaseSee end of main text.
Isami SogabeSee end of main text.
Thukaa KoukaSee end of main text.ORCID https://orcid.org/0000-0002-4442-2294
Elizabeth A WinzelerSee end of main text.
Iain B H WilsonSee end of main text.ORCID https://orcid.org/0000-0001-8996-1518
Matthew P CampbellSee end of main text.ORCID https://orcid.org/0000-0002-9525-792X
Sriram NeelameghamSee end of main text.
Frederick J KrambeckSee end of main text.ORCID https://orcid.org/0000-0003-3838-3775
Kiyoko F Aoki-KinoshitaSee end of main text.
Nathan E LewisSee end of main text.ORCID https://orcid.org/0000-0001-7700-3654

Funding

NIDDK Network Coordinating UnitU24DK097771 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Shuibing Chen, Jeffrey S. Grethe · 2013 to 2026
$20.9M
Systems Biology of GlycosylationR01HL103411 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI NEELAMEGHAM, SRIRAM · 2011 to 2025
$7.1M
Unraveling the mammalian secretory pathway through systems biology and algorithm developmentR35GM119850 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LEWIS, NATHAN ENOCH · 2016 to 2025
$4.3M
NHLBI NIH HHS R01 HL103411NIDDK NIH HHS U24 DK097771NIGMS NIH HHS R35 GM119850
6 · The paper itself

Abstract

Systems glycobiology aims to provide models and analysis tools that account for the biosynthesis, regulation, and interactions with glycoconjugates. To facilitate these methods, there is a need for a clear glycan representation accessible to both computers and humans. Linear Code, a linearized and readily parsable glycan structure representation, is such a language. For this reason, Linear Code was adapted to represent reaction rules, but the syntax has drifted from its original description to accommodate new and originally unforeseen challenges. Here, we delineate the consensuses and inconsistencies that have arisen through this adaptation. We recommend options for a consensus-based extension of Linear Code that can be used for reaction rule specification going forward. Through this extension and specification of Linear Code to reaction rules, we aim to minimize inconsistent symbology thereby making glycan database queries easier. With a clear guide for generating reaction rule descriptions, glycan synthesis models will be more interoperable and reproducible thereby moving glycoinformatics closer to compliance with FAIR standards. Here, we present Linear Code for Reaction Rules (LiCoRR), version 1.0, an unambiguous representation for describing glycosylation reactions in both literature and code.

Indexed as

glycoinformaticslinear codesystems glycobiology

Identifiers

PMID33178355
PMCPMC7607430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.