Evidence map›Paper›PMID 33178318›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2020

Efficacy and Safety of Acupuncture-Moxibustion Therapy on Chemotherapy-Induced Leukopenia: A Systematic Review and Meta-Analysis.

Huimin Jin, Yuqian Feng, Yuying Xiang, Yiting Zhang, Wurong Du, Harpreet S Wasan, Shanming Ruan, Dawei Huang

Open access · hybridAbstract readReview
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Acupuncture improves immunity and fatigue after chemotherapy in breast cancer patients by inhibiting the Leptin/AMPK signaling pathway.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Huimin JinFirst Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou 310051, Zhejiang, China.ORCID https://orcid.org/0000-0002-7720-3549
Yuqian FengFirst Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou 310051, Zhejiang, China.ORCID https://orcid.org/0000-0002-9912-7751
Yuying XiangFirst Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou 310051, Zhejiang, China.ORCID https://orcid.org/0000-0001-8991-7066
Yiting ZhangFirst Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou 310051, Zhejiang, China.ORCID https://orcid.org/0000-0002-6875-5632
Wurong DuFirst Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou 310051, Zhejiang, China.ORCID https://orcid.org/0000-0002-4414-7536
Harpreet S WasanDepartment of Cancer Medicine, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK.ORCID https://orcid.org/0000-0002-6268-2030
Shanming RuanDepartment of Medical Oncology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, Zhejiang, China.ORCID https://orcid.org/0000-0003-1061-5255
Dawei HuangDepartment of Chinese Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, Zhejiang, China.ORCID https://orcid.org/0000-0002-8669-0545
Zhejiang Chinese Medical University · CNImperial College Healthcare NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcupuncture-moxibustion therapy (AMT), as an integral part of complementary and alternative medicine, has been used for centuries in treatment of numerous diseases. Nevertheless, there is no available supportive evidence on the efficacy and safety of acupuncture-moxibustion therapy in patients with chemotherapy-induced leukopenia (CIL). The purpose of this study is to evaluate the efficacy and safety of acupuncture-moxibustion therapy in treating chemotherapy-induced leukopenia.

methodsRelevant studies were searched in nine databases up to September 19, 2020. Two reviewers independently screened the studies for eligibility, extracted data, and assessed the methodological quality of selected studies. Meta-analysis of the pooled mean difference (MD) and risk ratio (RR) with their respective 95% confidence intervals (CI) were calculated.

results17 studies (1206 patients) were included, and the overall quality of the included studies was moderate. In comparison with medical therapy, AMT has a better clinical efficacy for CIL (RR, 1.24; 95% CI, 1.17-1.32;

conclusionThis systematic review and meta-analysis provides updated evidence that AMT is a safe and effective alternative for the patients who suffered from CIL.

Identifiers

PMID33178318
PMCPMC7647756
OpenAlexW3094903973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.