Evidence map›Paper›PMID 33178284›Full record

ArticleCase reports in medicine2020

Epileptic Seizure Provoked by Bone Metastasis of Chronic Lymphoid Leukemia and Merkel Cell Carcinoma.

András Folyovich, Angéla Majoros, Tamás Jarecsny, Gitta Pánczél, Zsuzsanna Pápai, Gábor Rudas, Lajos Kozák, Gábor Barna, Katalin A Béres-Molnár, Károly Vadasdi and 3 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

András FolyovichDepartment of Neurology and Stroke, Szent János Hospital, Budapest, Hungary.
Angéla MajorosDepartment of Neurology and Stroke, Szent János Hospital, Budapest, Hungary.
Tamás JarecsnyDepartment of Neurology and Stroke, Szent János Hospital, Budapest, Hungary.
Gitta PánczélNational Institute of Oncology, Budapest, Hungary.
Zsuzsanna PápaiMilitary Hospital, Budapest, Hungary.
Gábor RudasMR Research Centre, Semmelweis University, Budapest, Hungary.
Lajos KozákMR Research Centre, Semmelweis University, Budapest, Hungary.
Gábor BarnaFirst Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary.
Katalin A Béres-MolnárDepartment of Neurology and Stroke, Szent János Hospital, Budapest, Hungary.
Károly VadasdiDepartment of Neurology and Stroke, Szent János Hospital, Budapest, Hungary.
Gabriella LiszkayNational Institute of Oncology, Budapest, Hungary.
Eszter HorváthDepartment of Neurology and Stroke, Szent János Hospital, Budapest, Hungary.
Gergely ToldiDepartment of Laboratory Medicine, Semmelweis University, Budapest, Hungary.ORCID https://orcid.org/0000-0003-0178-1243
Szent János Kórház · HUSemmelweis University · HUNational Institute of Oncology · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMerkel cell carcinoma (MCC) is a rare primary neuroendocrine cutaneous tumor, rarely metastasizing to the brain. Chronic lymphoid leukemia (CLL) is a disease predisposing to MCC. According to previous reports, headache and focal neurological deficits suggest disease progression to the brain. We present a patient with MCC whose seizure was not elicited by a cerebral metastasis, but by bone metastases compressing the brain.

conclusionsThe case history of the patient was unique even among the rare cases of MCC with neurological involvement. The seizure was not elicited by a cerebral metastasis, but by bone metastases compressing the brain. In addition to patient history, clinical presentation and radiological findings enabled a suspected diagnosis of skull metastasis of MCC compressing the brain, causing symptomatic epileptic seizures.

Identifiers

PMID33178284
PMCPMC7609155
OpenAlexW3096017564

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.