ArticleInternational journal of endocrinology2020
Sarcopenia in Type 2 Diabetes Mellitus: A Cross-Sectional Observational Study.
Article in International journal of endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Prevalence and risk factors of sarcopenia in Asian adults with type 2 diabetes: A systematic review and meta-analysis.Journal of diabetes investigation · 2026Pooled it
- Prevalence, risk factors and adverse health outcomes of osteosarcopenia in middle-aged and older adults with type 2 diabetes mellitus-a scoping review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Review
- Diabetes is associated with reduced grip strength: A cross-sectional study of medical check-up results in Japanese seniors.Journal of diabetes investigation · 2026Article
- Sarcopenia, body composition, physical performance, and clinical features in Parkinson's disease: a cross-sectional comparative study.Frontiers in endocrinology · 2026Article
- The Gut Microbiota-Muscle Axis: Lactobacillus as a Potential Modulator of Skeletal Muscle Health.BioMed research international · 2026Review
- Circulating Biomarkers as a Window into the Relationship between Sarcopenia and Diabetes: Implications for Effective Management.Current diabetes reviews · 2026Review
- Circulating Biomarkers as a Window into the Relationship between Sarcopenia and Diabetes: Implications for Effective Management.Current diabetes reviews · 2026Review
- Epigenetic inhibition of class I histone deacetylases by MS-275 attenuates diabetic skeletal muscle atrophy via Akt/ARK5-FoxO and myostatin-Smad signaling.Frontiers in endocrinology · 2026Article
- Relaxed Stiffness of Lower Extremity Muscles and Step Width Variability as Key Differences Between Sarcopenia and Dynapenia in Community-Dwelling Older Adults: A Cross-Sectional Study.Life (Basel, Switzerland) · 2025Article
- Melatonin protects against sarcopenia in middle-aged mice.Histology and histopathology · 2025Article
- Relationship Between Fat-to-Muscle Ratio and Nonalcoholic Fatty Liver Disease in Middle-Aged and Older Adults with Type 2 Diabetes: Cross-Sectional Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Evaluation of the Relationship Between Sarcopenia and the Geriatric Nutritional Risk Index in Elderly Patients With Type 2 Diabetes Mellitus.International journal of endocrinology · 2025Article
- Skeletal Muscle Mass Loss and Physical Function in Young to Middle-Aged Adult Patients With Diabetes: Cross-Sectional Observational Study.Interactive journal of medical research · 2024Article
- Sarcopenia-associated factors and their bone mineral density levels in middle-aged and elderly male type 2 diabetes patients.World journal of diabetes · 2024Article
- Sarcopenia in the foot on magnetic resonance imaging in patients with diabetes mellitus - a systematic review.Clinical diabetes and endocrinology · 2024Review
- Diabetes Mellitus Should Be Considered While Analysing Sarcopenia-Related Biomarkers.Journal of clinical medicine · 2024Review
- The Vicious Cycle of Type 2 Diabetes Mellitus and Skeletal Muscle Atrophy: Clinical, Biochemical, and Nutritional Bases.Nutrients · 2024Review
- Dynapenia and sarcopenia: association with the diagnosis, duration and complication of type 2 diabetes mellitus in ELSA-Brasil.Cadernos de saude publica · 2024Article
- The Relationship Between Sarcopenia And Proteinuria, What Do We Know?Current aging science · 2024Review
- Prevalence of Sarcopenia and Dynapenia and Related Clinical Outcomes in Patients with Type 1 Diabetes Mellitus.Nutrients · 2023Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to compare the prevalence of low muscle mass and sarcopenia in patients with type 2 diabetes mellitus (T2DM) versus paired controls (control group, CG) and the association between sarcopenia and chronic diabetes complications.
methodsMen and women ≥50 years with T2DM (T2DM group, T2DMG) were recruited during routine outpatient visits. Total body densitometry and handgrip strength (HGS) were evaluated in the T2DMG and CG, while the T2DMG was also evaluated for the physical performance using the gait speed (GS) test. Sarcopenia was diagnosed according to the criteria of the Foundation for the National Institutes of Health Sarcopenia Project (FNIH).
resultsThe study included 177 individuals in the T2DMG and 146 in the CG. The mean HGS value was lower in the T2DMG (24.4 ± 10.3 kg) compared with the CG (30.9 ± 9.15 kg),
conclusionPatients with T2DM presenting with albuminuria, osteoporosis, and increased %TF were more likely to have sarcopenia. This finding emphasizes the need for patients with T2DM to be evaluated for sarcopenia to allow for early implementation of measures to prevent or treat this disorder.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.