Evidence map›Paper›PMID 33178246›Full record

ArticleFrontiers in plant science2020

Novel Prodiginine Derivatives Demonstrate Bioactivities on Plants, Nematodes, and Fungi.

Samer S Habash, Hannah U C Brass, Andreas S Klein, David P Klebl, Tim Moritz Weber, Thomas Classen, Jörg Pietruszka, Florian M W Grundler, A Sylvia S Schleker

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

  1. Synthesis, Anthelmintic Activity, and Mechanism of Action of 5-Aryl-1Journal of agricultural and food chemistry · 2025
    Article
  2. Promising Prodiginins Biological Activities.Chemistry & biodiversity · 2025
    Review
  3. An Algerian Soil-LivingJournal of fungi (Basel, Switzerland) · 2024
    Article
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  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Samer S HabashINRES Molecular Phytomedicine, University of Bonn, Bonn, Germany.
Hannah U C BrassInstitute of Bioorganic Chemistry, Heinrich Heine University Düsseldorf, Forschungszentrum Jülich, Stetternicher Forst, Jülich, Germany.
Andreas S KleinInstitute of Bioorganic Chemistry, Heinrich Heine University Düsseldorf, Forschungszentrum Jülich, Stetternicher Forst, Jülich, Germany.
David P KleblInstitute of Bioorganic Chemistry, Heinrich Heine University Düsseldorf, Forschungszentrum Jülich, Stetternicher Forst, Jülich, Germany.
Tim Moritz WeberInstitute of Bioorganic Chemistry, Heinrich Heine University Düsseldorf, Forschungszentrum Jülich, Stetternicher Forst, Jülich, Germany.
Thomas ClassenIBG-1: Bioorganic Chemistry, Forschungszentrum Jülich GmbH, Jülich, Germany.
Jörg PietruszkaInstitute of Bioorganic Chemistry, Heinrich Heine University Düsseldorf, Forschungszentrum Jülich, Stetternicher Forst, Jülich, Germany.
Florian M W GrundlerINRES Molecular Phytomedicine, University of Bonn, Bonn, Germany.
A Sylvia S SchlekerINRES Molecular Phytomedicine, University of Bonn, Bonn, Germany.
Forschungszentrum Jülich · DEUniversity of Bonn · DEHeinrich Heine University Düsseldorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial metabolites represent an invaluable source of bioactive molecules which can be used as such or serve as chemical frameworks for developing new antimicrobial compounds for various applications including crop protection against pathogens. Prodiginines are tripyrrolic, red-colored compounds produced by many bacterial species. Recently, due to the use of chemical-, bio-, or mutasynthesis, a novel group of prodiginines was generated. In our study, we perform different assays to evaluate the effects of prodigiosin and five derivatives on nematodes and plant pathogenic fungi as well as on plant development. Our results showed that prodigiosin and the derivatives were active against the bacterial feeding nematode

Indexed as

natural productnematodeplant pathogensplant protectionprodiginines

Identifiers

PMID33178246
PMCPMC7596250
OpenAlexW3097059036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.