Evidence map›Paper›PMID 33178182›Full record

ArticleFrontiers in immunology2020

Possible Roles of Proinflammatory Signaling in Keratinocytes Through Aryl Hydrocarbon Receptor Ligands for the Development of Squamous Cell Carcinoma.

Yota Sato, Taku Fujimura, Takanori Hidaka, Chunbing Lyu, Kayo Tanita, Shigeto Matsushita, Masayuki Yamamoto, Setsuya Aiba

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yota SatoDepartment of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Taku FujimuraDepartment of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Takanori HidakaDepartment of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Chunbing LyuDepartment of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Kayo TanitaDepartment of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Shigeto MatsushitaDepartment of Dermato-Oncology/Dermatology, National Hospital Organization Kagoshima Medical Center, Kagoshima, Japan.
Masayuki YamamotoDepartment of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.
Setsuya AibaDepartment of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Tohoku University · JPKagoshima Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aryl hydrocarbon receptor (AhR) provides a deeper insight into the pathogenesis of cutaneous squamous cell carcinoma (cSCC). AhR ligands, such as 6-formylindolo[3,2-b] carbazole (FICZ), and 7,12-Dimethylbenz[a]anthracene (DMBA), constitute major substrates for the cytochrome P450 (CYP) family, and influence the expression of various cytokine genes, including

Indexed as

AnimalsAnthracenesCarbazolesCarcinoma, Squamous CellCytokinesHumansInflammationKeratinocytesMiceMice, Inbred BALB CMice, TransgenicNeoplasm ProteinsPiperidinesReceptors, Aryl HydrocarbonSignal TransductionSkin Neoplasms3-(2,6-bis(4-fluorophenyl)-3-methylpiperidin-4-ylideneamino)-2-thioxoimidazolidin-4-one on 7,12-dimethylbenz(a)anthracene6-formylindolo(3,2-b)carbazoleAnthracenesCarbazolesCytokinesNeoplasm ProteinsPiperidinesReceptors, Aryl Hydrocarbonaryl hydrocarbon receptorcarcinogenesiscutaneous SCCIL-17proinflammatory cytokines

Identifiers

PMID33178182
PMCPMC7596320
OpenAlexW3093193632

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.