Evidence map›Paper›PMID 33178164›Full record

ReviewFrontiers in microbiology2020

Antimicrobial Peptides: Classification, Design, Application and Research Progress in Multiple Fields.

Yuchen Huan, Qing Kong, Haijin Mou, Huaxi Yi

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05368948 (The Assessment of Antimicrobial Peptides Against Fungal Infection), which is not on this map. Cited by 761 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
761citing papers in PubMed, 1 pooled it
99.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05368948 unknown statusnot on this mapstarted 2022, after this paper: background citation

The Assessment of Antimicrobial Peptides Against Fungal Infection

TypeobservationalSponsorAssiut UniversityRan2022 to 2023Enrolled100ConditionsFungal Infection
3 · Its place in the literature

Who cites it

761 citing papers in PubMed, 1 synthesis or guideline pooled it, 1,500 citations in OpenAlex.

  1. Pooled it
  2. Effects of Antimicrobial Peptides on Bacterial Cells.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
  3. Review
  4. Review
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  6. Review
  7. Novel Peptide-Triazole Conjugates: Strategic Synthesis, Antimicrobial Properties, and Molecular Docking Study.Journal of peptide science : an official publication of the European Peptide Society · 2026
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
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  19. Review
  20. Adaptive Response ofAntibiotics (Basel, Switzerland) · 2026
    Article

701 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yuchen HuanCollege of Food Science and Engineering, Ocean University of China, Qingdao, China.
Qing KongCollege of Food Science and Engineering, Ocean University of China, Qingdao, China.
Haijin MouCollege of Food Science and Engineering, Ocean University of China, Qingdao, China.
Huaxi YiCollege of Food Science and Engineering, Ocean University of China, Qingdao, China.
Ocean University of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial peptides (AMPs) are a class of small peptides that widely exist in nature and they are an important part of the innate immune system of different organisms. AMPs have a wide range of inhibitory effects against bacteria, fungi, parasites and viruses. The emergence of antibiotic-resistant microorganisms and the increasing of concerns about the use of antibiotics resulted in the development of AMPs, which have a good application prospect in medicine, food, animal husbandry, agriculture and aquaculture. This review introduces the progress of research on AMPs comprehensively and systematically, including their classification, mechanism of action, design methods, environmental factors affecting their activity, application status, prospects in various fields and problems to be solved. The research progress on antivirus peptides, especially anti-coronavirus (COVID-19) peptides, has been introduced given the COVID-19 pandemic worldwide in 2020.

Indexed as

antimicrobial peptidesapplicationclassificationcoronavirusdesignmode of actionmotifs

Identifiers

PMID33178164
PMCPMC7596191
OpenAlexW3092909579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.