Evidence map›Paper›PMID 33178119›Full record

ArticleFrontiers in neurology2020

Feasibility of Using the Video-Head Impulse Test to Detect the Involved Canal in Benign Paroxysmal Positional Vertigo Presenting With Positional Downbeat Nystagmus.

Andrea Castellucci, Pasquale Malara, Salvatore Martellucci, Cecilia Botti, Silvia Delmonte, Silvia Quaglieri, Elisabetta Rebecchi, Enrico Armato, Massimo Ralli, Marco Lucio Manfrin and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Possible pathomechanism behind the transient hypofunction of the affected canal in BPPV. Letter to the editor regarding "Clinical significance of video head impulse test in benign paroxysmal positional vertigo: a meta-analysis" by Elsherif M et al. European Archives of Oto-Rhino-Laryngology (2021);278(12):4645-4651.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Pooled it
  2. Vestibular deficit and recovery in rare forms of benign paroxysmal positional vertigo with downbeat nystagmus.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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  17. Possible pathomechanism behind the transient hypofunction of the affected canal BPPV: reply to letter to the editor.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 2 countries.

Andrea CastellucciENT Unit, Department of Surgery, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Pasquale MalaraAudiology and Vestibology Service, "Centromedico Bellinzona", Bellinzona, Switzerland.
Salvatore MartellucciENT Unit, "Santa Maria Goretti" Hospital, Azienda USL Latina, Latina, Italy.
Cecilia BottiENT Unit, Department of Surgery, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Silvia DelmonteENT Unit, Department of Surgery, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Silvia QuaglieriENT Unit, Policlinico San Matteo Fondazione (IRCCS), Pavia, Italy.
Elisabetta RebecchiENT Unit, "Guglielmo da Saliceto" Hospital, Piacenza, Italy.
Enrico ArmatoENT Unit, "SS Giovanni e Paolo" Hospital, Venice, Italy.
Massimo RalliHead and Neck Department, ENT Clinic, Policlinico Umberto I, Rome, Italy.
Marco Lucio ManfrinENT Unit, Policlinico San Matteo Fondazione (IRCCS), Pavia, Italy.
Angelo GhidiniENT Unit, Department of Surgery, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Giacinto Asprella LibonatiVestibology and ENT Unit, "Giovanni Paolo II" Hospital, Matera, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITAzienda Sanitaria Unità Locale di Reggio Emilia · ITGuglielmo da Saliceto Hospital · ITOspedale San Paolo · ITOspedale Santa Maria Goretti · ITPoliclinico San Matteo Fondazione · ITSapienza University of Rome · ITScuola Cantonale di Commercio Bellinzona · CHUniversity of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Positional downbeat nystagmus (pDBN) represents a relatively frequent finding. Its possible peripheral origin has been widely ascertained. Nevertheless, distinguishing features of peripheral positional nystagmus, including latency, paroxysm and torsional components, may be missing, resulting in challenging differential diagnosis with central pDBN. Moreover, in case of benign paroxysmal positional vertigo (BPPV), detection of the affected canal may be challenging as involvement of the non-ampullary arm of posterior semicircular canal (PSC) results in the same oculomotor responses generated by contralateral anterior canal (ASC)-canalolithiasis. Recent acquisitions suggest that patients with persistent pDBN due to vertical canal-BPPV may exhibit impaired vestibulo-ocular reflex (VOR) for the involved canal on video-head impulse test (vHIT). Since canal hypofunction normalizes following proper canalith repositioning procedures (CRP), an incomplete canalith jam acting as a "low-pass filter" for the affected ampullary receptor has been hypothesized. This study aims to determine the sensitivity of vHIT in detecting canal involvement in patients presenting with pDBN due to vertical canal-BPPV. We retrospectively reviewed the clinical records of 59 consecutive subjects presenting with peripheral pDBN. All patients were tested with video-Frenzel examination and vHIT at presentation and after resolution of symptoms or transformation in typical BPPV-variant. BPPV involving non-ampullary tract of PSC was diagnosed in 78%, ASC-BPPV in 11.9% whereas in 6 cases the involved canal remained unidentified. Presenting VOR-gain values for the affected canal were greatly impaired in cases with persistent pDBN compared to subjects with paroxysmal/transitory nystagmus (

Indexed as

anterior semicircular canal BPPVapogeotropic BPPVbenign paroxysmal positional vertigo (BPPV)downbeat nystagmusposerior semicircular canal BPPVpositional nystagmusvestibulo-ocular reflex (VOR)video head impulse test (vHIT)

Identifiers

PMID33178119
PMCPMC7593380
OpenAlexW3092893419

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.