Evidence map›Paper›PMID 33177937›Full record

ArticleTurkish journal of pharmaceutical sciences2020

Citral Protects Human Endothelial Cells Against Hydrogen Peroxide-induced Oxidative Stress.

Leila Safaeian, Seyed Ebrahim Sajjadi, Hossein Montazeri, Farzaneh Ohadi, Shaghayegh Javanmard

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of pharmaceutical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Leila SafaeianIsfahan University of Medical Sciences, School of Pharmacy and Pharmaceutical Sciences, Department of Pharmacology and Toxicology, Isfahan Pharmaceutical Sciences Research Center, Isfahan, Iran.ORCID https://orcid.org/0000-0002-7811-3406
Seyed Ebrahim SajjadiIsfahan University of Medical Sciences, School of Pharmacy and Pharmaceutical Sciences, Department of Pharmacognosy, Isfahan, Iran.ORCID https://orcid.org/0000-0003-2155-1867
Hossein MontazeriIsfahan University of Medical Sciences, School of Pharmacy and Pharmaceutical Sciences, Department of Pharmacology and Toxicology, Isfahan Pharmaceutical Sciences Research Center, Isfahan, Iran.ORCID https://orcid.org/0000-0002-8415-5960
Farzaneh OhadiIsfahan University of Medical Sciences, Vice Chancellery for Food and Drugs, Office for Drug, Food, Cosmetics and hygienic Product's QC Laboratory, Isfahan, Iran.ORCID https://orcid.org/0000-0003-4336-7251
Shaghayegh JavanmardIsfahan University of Medical Sciences, Cardiovascular Research Institute, Applied Physiology Research Center, Isfahan, Iran.ORCID https://orcid.org/0000-0002-3853-5006
Isfahan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOxidative stress plays a major role in endothelial dysfunction. Citral is a monoterpene aldehyde with antioxidant properties. This study aimed to investigate the effect of citral on human umbilical vein endothelial cells (HUVECs) under hydrogen peroxide (H MATERIALS AND

methodsThe cells were treated with citral (0.625-10 μg/mL) for 24 h before exposure to H

resultsPretreatment of HUVECs with citral at concentrations of 5 and 10 μg/mL significantly enhanced the cell viability in H

conclusionAntioxidant and cytoprotective effects were found for citral against oxidative damage induced by H

Indexed as

antioxidantCitralHUVECshydrogen peroxideoxidative stress

Identifiers

PMID33177937
PMCPMC7650734
OpenAlexW2970254033

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.